Jason Lee set to work at once with zeal, patience, and intelligence, to inaugurate the work to which he had consecrated his life. At times his efforts seemed to be well rewarded. Then pestilence would attack the Indians, followed by suspicion and excitement, as a result of which all the gains would be lost. The work among the whites and their half-breed families was more encouraging than that with the Indians. At the best, Indians have been inconstant and unreliable in respect to religious instruction. In 1837 a strong reinforcement arrived, among whom were Dr. Elijah White, destined to become a man of note as Superintendent of Indian Affairs. In 1838, Rev. Daniel Lee and Rev. H. K. W. Perkins established a new station at Wascopum, now the location of The Dalles. In the same year Jason Lee returned East to secure an addition to the mission. His efforts were crowned with success. Five missionaries, one physician, six mechanics, four farmers, one steward, and four female teachers, with a number unclassified,--in all thirty-six adults and seventeen children,--reached the Columbia River on the good ship _Lausanne_, under charge of Captain Spalding, on May 21, 1840. This was the most notable company that had yet reached our Great River. Among them were men and women who contributed in a great degree to the subsequent growth of Oregon. Of the number were Revs. Gustavus Hines, Alvin Waller, J. P. Richmond, and J. H. Frost; Dr. Ira L. Babcock, George Abernethy, afterwards governor of the territory, J. L. Parrish, and L. H. Judson. All the men were accompanied by their wives, and most of them had children. They were, in short, the advance guard of the American home-builders in Oregon, and as such they deserve a special place on the roll of honour. With this added force, it was possible to enlarge the work, in both secular and religious lines, both among the whites and the Indians. A mission was started at Clatsop on the south side of the mouth of the Columbia under Mr. Parrish, one at the falls of the Willamette, and another on Tualatin Plains, under Mr. Hines, while still another was located by Mr. Richmond at Nisqually on Puget Sound. As time passed on, it became more and more evident that this work was to become less for Indians and more for the incoming whites. The whole aspect of it changed. The Methodist Board in New England decided that they were not justified in maintaining the missions, and these were discontinued during the decade of the forties. Out of the mission at Chemeketa grew Willamette University, one of the most prominent educational institutions of Oregon.