These settlers of the Valley of Virginia and the North Carolina piedmont region--English, Scotch-Irish, Germans, Scotch, Irish, Welsh, and a few French--were the first pioneers of the Old Southwest. From the joint efforts of two strata of population, geographically, socially, and economically distinct--tidewater and piedmont, Old South and New South--originated and flowered the third and greatest movement of westward expansion, opening with the surmounting of the mountain barrier and ending in the occupation and assumption of the vast medial valley of the continent. Synchronous with the founding of Jamestown in Virginia, significantly enough, was the first planting of Ulster with the English and Scotch. Emigrants from the Scotch Lowlands, sometimes as many as four thousand a year (1625), continued throughout the century to pour into Ulster. "Those of the North of Ireland...," as pungently described in 1679 by the Secretary of State, Leoline Jenkins, to the Duke of Ormond, "are most Scotch and Scotch breed and are the Northern Presbyterians and phanatiques, lusty, able-bodied, hardy and stout men, where one may see three or four hundred at every meeting-house on Sunday, and all the North of Ireland is inhabited by these, which is the popular place of all Ireland by far. They are very numerous and greedy after land." During the quarter of a century after the English Revolution of 1688 and the Jacobite uprising in Ireland, which ended in 1691 with the complete submission of Ireland to William and Mary, not less than fifty thousand Scotch, according to Archbishop Synge, settled in Ulster. Until the beginning of the eighteenth century there was no considerable emigration to America; and it was first set up as a consequence of English interference with trade and religion. Repressive measures passed by the English parliament (1665-1699), prohibiting the exportation from Ireland to England and Scotland of cattle, beef, pork, dairy products, etc., and to any country whatever of manufactured wool, had aroused deep resentment among the Scotch-Irish, who had built up a great commerce. This discontent was greatly aggravated by the imposition of religious disabilities upon the Presbyterians, who, in addition to having to pay tithes for the support of the established church, were excluded from all civil and military office (1704), while their ministers were made liable to penalties for celebrating marriages.