Bodily agony long borne produces death by exhaustion. More frequently, arresting the action of the heart for a time, it causes that temporary death we call fainting. On other occasions vomiting is a consequence. And where such manifest derangements do not result, we still, in the pallor and trembling, trace the general prostration. Beyond the actual loss of life caused by subjection to intense cold there are depressions of vitality less marked caused by cold less extreme--temporary enfeeblement following too long an immersion in icy water; enervation and pining away consequent on inadequate clothing. Similarly is it with submission to great heat: we have lassitude reaching occasionally to exhaustion; we have, in weak persons, fainting, succeeded by temporary debilitation; and in steaming tropical jungles Europeans contract fevers which, when not fatal, often entail life-long incapacities. Consider, again, the evils that follow violent exertion continued in spite of painful feelings--now a fatigue which destroys appetite or arrests digestion if food is taken, implying failure of the reparative processes when they are most needed; and now a prostration of the heart, here lasting for a time and there, where the transgression has been repeated day after day, made permanent: reducing the rest of life to a lower level. No less conspicuous are the depressing effects of emotional pains. There are occasional cases of death from grief; and in other cases the mental suffering which a calamity causes, like bodily suffering, shows its effects by syncope. Often a piece of bad news is succeeded by sickness; and continued anxiety will produce loss of appetite, perpetual indigestion and diminished strength. Excessive fear, whether aroused by physical or moral danger, will, in like manner, arrest for a time the processes of nutrition; and, not unfrequently, in pregnant women brings on miscarriage; while, in less extreme cases, the cold perspiration and unsteady hands indicate a general lowering of the vital activities, entailing partial incapacity of body or mind or both. How greatly emotional pain deranges the visceral actions is shown us by the fact that incessant worry is not unfrequently followed by jaundice. And here, indeed, the relation between cause and effect happens to have been proved by direct experiment. Making such arrangements that the bile-duct of a dog delivered its product outside the body, Claude Bernard observed that so long as he petted the dog and kept him in good spirits, secretion went on at its normal rate; but on speaking angrily, and for a time so treating him as to produce depression, the flow of bile was arrested.