Gracious Ladies, so often as I consider with my selfe, and observe respectively, how naturally you are enclined to compassion; as many times do I acknowledge, that this present worke of mine, will (in your judgement) appeare to have but a harsh and offensive beginning, in regard of the mournfull remembrance it beareth at the verie entrance of the last Pestilentiall mortality, universally hurtfull to all that beheld it, or otherwise came to knowledge of it. But for all that, I desire it may not be so dreadfull to you, to hinder your further proceeding in reading, as if none were to looke thereon, but with sighes and teares. For, I could rather wish, that so fearefull a beginning, should seeme but as an high and steepy hill appeares to them, that attempt to travell farre on foote, and ascending the same with some difficulty, come afterward to walk upon a goodly even plaine, which causeth the more contentment in them, because the attaining thereto was hard and painfull. For, even as pleasures are cut off by griefe and anguish; so sorrowes cease by joyes most sweete and happie arriving. After this breefe molestation, briefe I say, because it is contained within small compasse of Writing; immediately followeth the most sweete and pleasant taste of pleasure, whereof (before) I made promise to you. Which (peradventure) could not bee expected by such a beginning, if promise stoode not thereunto engaged. And indeed, if I could wel have conveyed you to the center of my desire, by any other way, then so rude and rocky a passage as this is, I would gladly have done it. But because without this Narration, we could not demonstrate the occasion how and wherefore the matters hapned, which you shall reade in the ensuing Discourses: I must set them downe (even as constrained thereto by meere necessity) in writing after this manner. The yeare of our blessed Saviours incarnation, 1348. that memorable mortality happened in the excellent City, farre beyond all the rest in _Italy_; which plague, by operation of the superiour bodies, or rather for our enormous iniquities, by the just anger of God was sent upon us mortals. Some few yeeres before, it tooke beginning in the Easterne partes, sweeping thence an innumerable quantity of living soules: extending it selfe afterward from place to place Westward, untill it seized on the said City. Where neither humane skill or providence, could use any prevention, notwithstanding it was cleansed of many annoyances, by diligent Officers thereto deputed: besides prohibition of all sickly persons enterance, and all possible provision dayly used for conservation of such as were in health, with incessant prayers and supplications of devoute people, for the asswaging of so dangerous a sicknesse.