I afterwards found that this same idea had long ago occurred to Dr. Wells. (56. See a paper read before the Royal Soc. in 1813, and published in his Essays in 1818. I have given an account of Dr. Wells’ views in the Historical Sketch (p. xvi.) to my ‘Origin of Species.’ Various cases of colour correlated with constitutional peculiarities are given in my ‘Variation of Animals and Plants under Domestication,’ vol. ii. pp. 227, 335.) It has long been known that negroes, and even mulattoes, are almost completely exempt from the yellow-fever, so destructive in tropical America. (57. See, for instance, Nott and Gliddon, ‘Types of Mankind,’ p. 68.) They likewise escape to a large extent the fatal intermittent fevers, that prevail along at least 2600 miles of the shores of Africa, and which annually cause one-fifth of the white settlers to die, and another fifth to return home invalided. (58. Major Tulloch, in a paper read before the Statistical Society, April 20, 1840, and given in the ‘Athenaeum,’ 1840, p. 353.) This immunity in the negro seems to be partly inherent, depending on some unknown peculiarity of constitution, and partly the result of acclimatisation. Pouchet (59. ‘The Plurality of the Human Race’ (translat.), 1864, p. 60.) states that the negro regiments recruited near the Soudan, and borrowed from the Viceroy of Egypt for the Mexican war, escaped the yellow-fever almost equally with the negroes originally brought from various parts of Africa and accustomed to the climate of the West Indies. That acclimatisation plays a part, is shewn by the many cases in which negroes have become somewhat liable to tropical fevers, after having resided for some time in a colder climate. (60. Quatrefages, ‘Unité de l’Espèce Humaine,’ 1861, p. 205. Waitz, ‘Introduction to Anthropology,’ translat., vol. i. 1863, p. 124. Livingstone gives analogous cases in his ‘Travels.’) The nature of the climate under which the white races have long resided, likewise has some influence on them; for during the fearful epidemic of yellow fever in Demerara during 1837, Dr. Blair found that the death-rate of the immigrants was proportional to the latitude of the country whence they had come. With the negro the immunity, as far as it is the result of acclimatisation, implies exposure during a prodigious length of time; for the aborigines of tropical America who have resided there from time immemorial, are not exempt from yellow fever; and the Rev. H.B. Tristram states, that there are districts in Northern Africa which the native inhabitants are compelled annually to leave, though the negroes can remain with safety.