The diagnostics and treatment of tropical diseasesStitt, E. R. (Edward Rhodes)
Science
The diagnostics and treatment of tropical diseases
Stitt, E. R. (Edward Rhodes)
Tropical medicine
In Romanowsky-stained preparations we see, while the fever is
sustained, small hair-like rings, with geometrical outline, with
frequently two chromatin dots in one end of the ring and a single
red cell often showing two or more of these young rings. The rings
are often seen as if plastered on the periphery of the red cells
or as if having destroyed a rounded section of the rim of the
red cell. As the fever declines the rings tend to disappear from
the peripheral circulation. The infected red cells often show
polychromatophilia and distortion.
[Illustration: FIG. 8.—Tertian malarial parasite, one red cell
showing malarial stippling. (Todd.)
FIG. 9.—Estivo-autumnal malarial parasites, and small
ring forms and crescents. (Todd.)]
In old aestivo-autumnal cases, or those with severe infection, we
may see adult rings and merocytes, which latter are smaller than
those of benign tertian, show from 10 to 12 irregularly placed
merozoites and a sharply clumped mass of pigment.
The gametes are the striking crescent-shaped bodies and these show
the distinctions of blue-staining for the female, with lighter
gray-blue to purplish staining and abundance of chromatin for
the male. The chromatin staining of crescents does not stand out
so well as that of the round form gametes of benign tertian and
quartan.
The black pigment of the female tends to be clumped toward the
center while the rather generally distributed pigment of the male
is reddish brown rather than black in a stained preparation.
This variation of pigment color may be due to the effect of
chromatin staining, as the black of the pigment is the same in male
and female gametes in fresh blood preparations.
_Stained Smear Preferred._—As regards differentiation of species
and cycle the examination of stained smears is more satisfactory and
definite, as well as less time consuming. Still, one obtains many
points of differentiation in the fresh preparation and should study
such a preparation while carrying out the staining of his dried smear.
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