This was about the first definitely proven connection between water and cholera. In 1854 it was noted that cholera was about 10 times as prevalent in Golden Square as in other adjacent parts of London. Various factors, such as previous droughts, stagnation of lower strata of the atmosphere, sewerage defects and subsoil drainage were found to be the same in Golden Square as elsewhere. It was noted that the number of cases increased in the neighborhood of the Broad Street well. The employees of a cartridge factory where this well water was used gave a large number of cases while an adjoining brewery, which had a well of its own and served out beer to its employees, did not furnish a single case. Very striking was the case of a lady living at Hampstead, a section of London which was then free from cholera, who had acquired a liking for the water of this well and had brought out to her regularly bottles of water from the well. This lady drank some of the water on August 31 and was seized with cholera the next day. A niece drank of the same water and died of cholera as well as the aunt. A servant also contracted the disease but recovered. Macnamara has noted the circumstance of a vessel of water, which became contaminated with cholera stools, but which at the time it was drunk by 19 persons did not show anything suspicious in odor, color or taste. One person was stricken one day afterward, two on the third day and two others came down with cholera on the fourth day. It will be noted that only 5 of the 19 were attacked. A similar lack of susceptibility of a certain proportion of people, equally exposed, has been noted in all cholera outbreaks. It is probable that of those of the 19 who did not contract cholera there were developed a certain number of cholera carriers. _Food Transmission._—Food contaminated by dejecta from cholera patients or carriers is dangerous in proportion to its condition of moisture. Drying and the development of inimical organisms are the two chief factors in destroying the cholera vibrio. Temperature and sunshine are operative in assisting the drying process. Lettuce and celery are particularly dangerous because of the favorable condition of moisture in their folds and imbrications. Furthermore these vegetables are eaten uncooked and may have been fertilized with night soil (human excrement) which material, if containing cholera dejecta, would infect the plants. Milk is a splendid culture medium for cholera vibrios but, upon becoming acid, sterilizes itself of these vibrios. In sterilized milk, however, they live for extended periods, as long as sixty days and, even when such milk is contaminated by faecal material containing other organisms besides the cholera vibrio, the vibrios live much longer than they do in raw milk.