_Prolonged Continuation of Faulty Diet Necessary._—It appeared that a considerable period of continuance of white rice diet was necessary before the appearance of the disease (eighty-seven days). As against the infectious nature of the disease they note that contact of persons on a parboiled rice diet with the beriberi cases was without result. Substitution of parboiled rice for white rice brought about a cessation of the outbreak. The Philippine scouts, numbering about 5000 natives, gave 618 cases of beriberi in 1908 and 550 cases in 1909. In 1910 undermilled rice was substituted for polished rice and they were required to eat 1-6 oz. beans daily. No other change in their mode of living was made. By 1913 beriberi had disappeared among them, although the disease still prevailed among the native population in contact with them. _Experiment of Strong and Crowell._—Strong and Crowell stated that the object of their study was to determine whether beriberi, as it occurs in the Philippines, is an infectious disease or whether it is one which has its origin in disturbances of metabolism, due chiefly to the prolonged use of polished rice as a staple article of diet. The experiments were carried out in Bilibid prison. Prisoners, who had been condemned to death, were informed of the nature of the experiment and were told of the diet on which it was proposed to place them. They were also told that they might contract beriberi. Twenty-nine volunteered and each signed a statement in his own dialect that he undertook the experiment voluntarily. In general, the groups were fed for the greater part of the time occupied by the experiments as follows: Group (1) “White rice and extract of rice polishings and special diet.” Group (2) “White rice and special diet.” Group (3) “Red rice and special diet.” Group (4) “White rice and special diet.” Of 6 men on the Group 1 diet, 2 developed beriberi. The symptoms however, were not marked, being chiefly loss of weight, tachycardia, slight oedema of legs and tenderness of muscles of calves. Four of the 6 men of Group 2 developed beriberi and 6 out of 11, in Group 4, showed symptoms of beriberi. In Group 3, only 2 in 6 developed symptoms and these consisted in case No. 13 only in tenderness of epigastrium, paraesthesia, cardiac disturbance and marked diminution of knee jerk. In case No. 18 there was noted only slight cardiac disturbance and epigastric pulsation. In none of the cases was the complete picture of beriberi obtained except in those in which the white polished rice formed the staple article of diet, but in one case, fed on red rice, the diagnosis of beriberi was almost definite.