I am not a physician, I am even ignorant of the simplest forms of disease which many druggists are familiar with, and my excuse for the ignorance is, that I have studiously avoided that line of study, that I might have less incentive for the so-called art of counter prescribing. But if I am weak in the knowledge of disease, I hope I have not spent thirty years behind the drug counter without using my faculties of observation, and in as short a time as possible, I wish to register my emphatic objection to the further open sale and use of the coal tar derivatives, and I follow with my reasons. My first notice of their danger was brought to me 25 years ago, in the early days of Acetanilid, by a physician, who gave large doses, and was enthusiastic over the results, and saw no harm in its use. A few months later I noticed that the doses had been cut down 65 per cent., and I enquired the cause. “Well,” says he, “I nearly killed half a dozen of my best friends, and I thought it time to stop.” As the years rolled on, scarcely a month passed by, but what some incident occurred that told me we have admitted into common use the most dangerous drugs ever placed upon the pages of our text books. I have taken 2½ grain doses of acetphenetidin with salol at various times for colds and rheumatism, and thought for years that it did me no harm, but now I am reluctantly compelled to acknowledge the contrary. For after two or three days’ use, with a dosage of 2½ grains three or four times a day I find myself almost completely benumbed and heart action very weak. And as I recall it I have always had these symptoms, though less pronounced, and yet it has taken years, with all my knowledge of the drug, to tumble to its viciousness. A physician very near to me, commenced using the same drug in small doses and in a short time could take as high as one dram, but he has quit. Here are the two extremes in dosage. Another physician gave a colored woman the well-known mixture of soda acetanilid and caffeine and in a short time she was consuming one ounce every two weeks. The physician and woman are both dead.