“The disease no sooner appeared, than it spread with rapidity through the medium of the principle of imitation; thus it was not uncommon for an affected person to communicate it to the greater part of a crowd, who, from curiosity or other motives, had collected around him. It is at this time, in almost every part of Tennessee and Kentucky, and in various parts of Virginia, but is said not to be contagious (or readily communicated) as at its commencement. It attacks both sexes, and every constitution, but evidently more readily those who are enthusiasts in religion, such as those above described, and females; children of six years of age, and adults of sixty, have been known to have it, but a great majority of those affected are from fifteen to twenty-five. The muscles generally affected are those of the trunk, particularly of the neck, sometimes those of the superior extremities, but very rarely, if ever, those of the inferior. The contractions are sudden and violent, such as are denominated convulsive, being sometimes so powerful, when in the muscles of the back, that the patient is thrown on the ground, where, for some time, his motions more resemble those of a live fish, when thrown on land, than any thing else to which I can compare them. “This, however, does not often occur, and never, I believe, except at the commencement of the disease. The patients, in general, are capable of standing and walking, and many, after it has continued a short time, can attend to their business, provided it is not of a nature requiring much steadiness of body. They are incapable of conversing with any degree of satisfaction to themselves or company, being continually interrupted by those irregular contractions of their muscles, each causing a grunt, or forcible expiration; but the organs of speech do not appear to be affected, nor has it the least influence on the mind. They have no command over their actions by any effort of volition, nor does their lying in bed prevent them, but they always cease during sleep. This disease has remissions and exacerbations, which, however, observe no regularity in their occurrence or duration. During the intermission a paroxysm is often excited at the sight of a person affected, but more frequently by the common salute of shaking hands. The sensations of the patients in a paroxysm are generally agreeable, which the enthusiastic class often endeavour to express, by laughing, shouting, _dancing_, &c.