These pieces or chromosomes become shorter by slowly contracting,
and thus each takes the form of an angular loop, a straight rod, or
a roundish, oval, or spherical body (Fig. 74, _C_, _chrs_). While
this is happening, we can see at the side of the nucleus, and closely
apposed to it, a pale longitudinally striped figure with a swelling,
similar to a handle, at both ends--the so-called nuclear spindle or
central spindle (_ksp_). This is the apparatus for the division of the
nucleus, and it was previously represented by a small body susceptible
to certain stains--the centrosome, which was surrounded by a halo-like
zone, the centrosphere or 'sphere.' This body was long overlooked,
but now the majority of investigators assume that, though it is often
inconspicuous and very difficult to make visible, it is nevertheless
present in every cell which is capable of division, and that it is
therefore a permanent and indispensable constituent of the cell (Fig.
74, _A_ and _B_, _csph_).
When a cell is on the point of dividing, this remarkable cell-organ,
which has hitherto seemed no more than an insignificant, pale, little
sphere, now becomes active. First of all, often before the formation
of the chromatin coil, it doubles by division (_A_ and _B_ _csph_), at
first only as regards the centrosome, and then as regards the sphere
also (_B_); and while division is going on fine protoplasmic filaments
issue from the dividing sphere and radiate like rays from a sun into
the cell-substance. As they only retain their connexion with each other
at the surfaces of the dividing halves of the sphere which are turned
towards each other, we might almost say that fine threads are drawn out
between the two halves as they separate, and these become longer the
further apart the halves diverge. In this manner the much-talked-of
'spindle figure' arises, which was first described in the seventies
through the researches of A. Schneider, Auerbach, and Bütschli, but the
significance and origin of which have claimed the labours of many later
investigators down to our own day.
The processes now to be described do not always take place in exactly
the same manner, but the gist of the business is everywhere the same,
and it consists in this, that the two ends or 'poles' of the spindle
diverge further and further apart, and between them lies the nucleus
whose membrane now disappears (_C_, _km_) while the spindle threads
traverse its interior. Sometimes the membrane is retained, but
nevertheless the spindle threads penetrate into the interior of the
nucleus. But the chromosomes always range themselves quite regularly
in the 'equatorial plane' of the spindle (_D_, _aeq_)--a process the
precise mechanism of which is by no means clearly understood, and
indeed the play of the forces in the whole process of nuclear division
is still very imperfectly revealed to our intelligence.
Public-domain text, read in full here on John Shaqi.
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