Thus we have now before us a pale, spindle-shaped figure, which takes
only a faint stain, with the 'suns' (_cs_) at its 'poles,' and in its
equatorial plane the loop- or rod-shaped, or spherical chromosomes
(_chrs_). The whole is designated the 'karyokinetic,' the 'mitotic,' or
the 'nuclear division figure.'
The meaning and importance of this, at first sight, puzzling figure
will at once become clear from what follows. It may be observed at this
stage, if not even long before, that each of the chromatin rods or
loops has split along its whole length like a log of wood, and that the
split halves are beginning slowly and hardly noticeably to move away
from each other, one half towards one, the other towards the other pole
of the spindle (Fig. _D_ and _F_). Directly in front of the centrosome
they make a halt, and now the material for the two daughter-nuclei
is in its proper place (_F_, _chrs_). These develop quickly, each
chromosome group surrounding itself with a nuclear membrane (Fig.
_G_) within which the chromosomes gradually become transformed again
into a nuclear network. Within the chromatin substance proper this is
scattered about in small roundish or angular granules, lying especially
at the intersecting points of the network. It may be stated at once,
though the full significance of the statement can only be appreciated
later, that we may assume with probability that this breaking up of the
chromosomes is only apparent, and that these rods or spheres really
continue to exist in the nuclear network, only in a different form,
greatly spread out, somewhat after the manner of a Rhizopod which
stretches out fine processes in all directions. These processes branch
and anastomose, so that the body, which previously seemed compact,
now appears as a fine network. In point of fact, it can be directly
observed that the chromosomes, after the nucleus is completely divided
into two daughter-nuclei, send out pointed processes (_F_ and _G_)
which gradually increase in length and branch, while the body of the
chromosome itself becomes gradually smaller. It is thus probable
that, when such a daughter-nucleus is on the point of dividing anew,
it may, by a drawing together of the processes or pseudopodia of the
chromosomes, produce the same rods or spheres as those which previously
gave rise to the network. More definite reasons for this interpretation
will be adduced later on. In any case, the chromosomes, even in
their compact rod-like state, consist of two kinds of substance,
the chromatin proper, which stains deeply, and the linin, which is
difficult to stain; and it is the latter which, by breaking up, forms
the pale part of the nuclear network.
Public-domain text, read in full here on John Shaqi.
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