Take of sarsaparilla root, coltsfoot root, or wild ginger root, sassafras root, dogwood root, yellow poplar root, prickley ash root, spicewood root, one handful of each, when dried, as much as you can hold in one hand; cut the bark off of the roots and pulverize as fine as you can, except the sarsaparilla, which must be cut in very small pieces; then put the whole in one gallon of best fourth-proof old rye whiskey, and let it stand for 1 or 2 weeks; but should you wish to use immediately, set the vessel containing the ingredients on the stove, and keep just warm for 2 or 3 days, when it will be fit for use. DIRECTIONS FOR USE. Take from 1 to 3 tablespoonsful 3 times a day, one hour before meals. It may be taken 5 or 6 times a day provided it does not affect the nerves too much. It is perfectly safe and has cured more cases of rheumatism than any other remedy introduced. I will cite one or two cases where it effected complete cures: Mr. Joshua Deer, who had been in a most helpless condition for a long time, and had tried many other remedies in vain, was cured in five days after he commenced using it, so as to be able to take a ride on horseback, which can be certified by a number of persons living in the neighborhood. Any one doubting the above, can have it proven to their satisfaction by addressing Ezra Deer, or Henry Gross, who was cured by it in less time. Let it be understood that there never was a preparation that would cure all cases: no, not one-fourth, therefore I have given a number of preparations, so that if one fail, others may prove efficacious, though the above remedy occupies the head of the list in our own estimation. Never give up any one remedy until you have given it a fair trial. “He that holds out faithfully shall be saved.” This medicine can be distilled the same as the cholera medicine, bottled up and kept for years. Mr. Joshua Deer, was cured with the distilled. Henry Gross and others used it in liquor. You must keep from labor and exposure, while using the above and be careful not to eat any thing greasy, or that which will not agree with you. FOR RHEUMATISM. Take 1 ounce of saltpetre, 1 quart of ale--if ale cannot be had take whiskey or water--dissolve the saltpetre in the ale. DIRECTIONS FOR USE. Take 1 wine glassful before breakfast, 1 before dinner, 1 before going to bed, and continue until relieved. Should the second quart do no good, stop taking it. You must keep from labor and exposure while using the above. Mr. Dill was cured by this remedy, who had suffered for more than a year constantly. FOR RHEUMATISM. Take 1 ounce of sulphur, 1¼ ounces of saltpetre, ½ ounce of gum guscomb, 2 nutmegs, the whole to be finely pulverized, to which add 12 ounces of molasses. DIRECTIONS FOR USE. Take 1 tea spoonful every night before going to bed, but if it should act too free on the bowels, the quantity must be diminished. LINIMENT FOR RHEUMATISM.