On the 14th of September 1523 Adrian VI. died in Rome after a short illness, and was buried in the church of Santa Maria dell'Anima. His death again raised Wolsey's hopes of the Papacy. Although Margaret sincerely mourned the loss of her old friend, still she lost no time in doing her utmost to procure the English cardinal's election. De Praet, writing from London to the emperor on the 6th of October, says: 'Moreover, Sire, I have to inform your Majesty that I have received letters from madame (Margaret), dated the 25th of last month, containing the afflicting news of the decease of the Holy Father, which took place on the 14th of the said month, commanding me on this account to repair without delay to the said cardinal (Wolsey) to give him as it may so happen the first intelligence of this event, and to offer him on her part all the favour and assistance in her power towards his promotion to this dignity. This I lost no time in doing according to her order, as well on the part of your Majesty as on hers; to which he made the most grateful and suitable reply, expressing his profound thanks to madame for such demonstrations of her goodwill in offering her services for his advancement to a dignity of which he felt himself utterly unworthy. 'Nevertheless, in acknowledging her gracious intentions, he could not but bear in mind in what manner your Majesty, when with the king at Windsor, had touched upon this subject, exhorting him to think of it, and promising every possible aid on your part in bringing about its accomplishment. 'He expressed the willingness of one who was always ready to conform with the wishes and advice of both your Majesties, begging that madame, in case such a promotion and election should appear to her as tending to the benefit of Christendom, and to the common interests of your Majesties, would write without a moment's delay to your ambassador in Rome, and to other of your good friends there....'[89] [89] W. Bradford.