Should small doses upset the stomach, in very susceptible persons, then it may be given by hypodermic injection, using the more soluble salts of QUININE, the Lactate a white powder soluble in 1 to 5 of water, or the Acid Hydrochloride of the B P[2]; in the U S P[3] it is the Di-chloride, which is soluble in less than its own weight of water; if small doses of Quinine cause headache and ringing in the ears in a well person than the remedy is unsuitable and should not be taken, for it will not prevent an attack of the Flu in that person. Footnote 2: British Pharmacopeia. Footnote 3: U. S. A. Pharmacopeia. Professor Dittmar Finkler, M.D., of the university of Bonn, Rhenish Prussia, in his work on Influenza, cites the experiments carried out by Dr. Graser, Medical Army Corps, on duty at the cavalry barracks at Bonn, where five squadrons of German cavalry were quartered during an Epidemic of Flu; one of the squadrons, complement of men, was given daily rations of Quinine for several weeks during the prevalence of the epidemic, the other four squadrons received no Quinine; the results are here set forth: Squadron Complement “Flu” Cases Quinine First 135 22 None Second 135 4 0.5 gm. daily Third 135 19 None Fourth 135 42 None Fifth 135 32 None It is reasonable to assume, that the food or pabulum of the bacillus of Influenza is poisoned by Quinine entering the blood, hence the microbe will avoid by instinct any person whose blood contains quinine in solution; if the bacillus has gained access to the system it is speedily destroyed, and becomes cadaveric as soon as it enters the zone of the quinine barrage. Are there Hours of the day when the System is more susceptible to Invasion by the Bacillus Influenzae? To determine this question requires careful study, time, a great deal of patient and tedious work and perseverance; yet it is possible to gain some information on this phase of the “Flu.” At intervals, during the past twenty-one years, from more than 1000 cases of Influenza in adults, the Author has managed to collect 132 cases; wherein, it was possible to check and verify with some degree of accuracy, the time of contact with a known source of Flu; no subsequent contact being had with any other known source of that disease. Material evidence was collected from isolated plantation camps, sparsely inhabited villages, and the suburbs of Honolulu at such times as there was no epidemic of Flu. A record of cases collected mostly in the autumn and winter months, from October to March, is hereunder set forth: Hours of Contact Cases Incubation Pneumonia 5 a.m. to 8 a.m. 30 2 to 3 days. None. 8 a.m. to 6 p.m. 22 2 to 3 days. None. 6 p.m. to 10 p.m. 80 1 to 5 days. 9