Even a loaded bowel may, as is well known, alter the reaction to life. Among men who are coarse in their language there is a salutation more pertinent than elegant that inquires into the state of the bowels.[1] The famous story of Voltaire and the Englishman, in which the sage agreed to suicide because life was not worth living when his digestion was disordered and who broke his agreement when he purged himself, illustrates how closely mood is related to the intestinal tract. And mood is the background of the psychic life, upon which depends the direction of our thoughts, cheerful or otherwise, the vigor of our will and purpose. Mood itself arises in part from the influences that stream into the muscles, joints, heart, lungs, liver, spleen, kidneys, digestive tract and all the organs and tissues by way of the afferent nerves (sympathetic and cerebro-spinal). Mood is thus in part a reflection of the health and proper working of the organism; it is the most important aspect of the subconsciousness, and upon it rests the structure of character and personality. [1] What is called coarse is frequently crudely true. Thus, in the streets, in the workshops, and where men untrammeled by niceties engage in personalities the one who believes the other to be a "crank" informs him in crude language that he has intestinal stasis (to put the diagnosis in medical language) and advises him accordingly to "take a pill." This does not mean that only the healthy are cheerful, or that the sick are discouraged. To affirm the dependence of mind upon body is not to deny that one may build up faith, hope, courage, through example and precept, or that one may not inherit a cheerfulness and courage (or the reverse). "There are men," says James, "who are born under a cloud." But exceptional individuals aside, the mass of mankind generates its mood either in the tissues of the body or in the circumstances of life. Children, because they have not built up standards of thought, mood and act, demonstrate in a remarkable manner the dependence of their character upon health.