study of the symptoms during life, and the effect of remedies upon them. It is hardly a sufficient justification of a man of so much independence of spirit to reply, that such examinations were opposed by the prejudices of the age in which he lived. Others have overcome the same obstacles, and with them many of those difficulties which perplexed and misled even the mind of Sydenham. He had equal or greater difficulties to contend against in the deep-rooted absurdities of the chemical and mechanical schools, which in the early part of his life held an almost equally divided sway in medicine: the former originated with Paracelsus and his disciples, and had the advantage of a longer prescription; and the latter had received a fresh accession of strength from the recent discoveries of Harvey: both, however, gave way before his energetic appeal to fact and experience. Scarcely less credit is due to him for his successful opposition to the popular superstition in favour of a host of futile remedies, which are now happily consigned to oblivion with the family receipt books and herbals in which their virtues were paraded, than for his victory over false principles and dangerous rules of practice. On the whole, it may be safely advanced that medicine, as a practical science, owes more to the closely-printed octavo, in which the results of his toilsome exertions are comprised, than to any other single source of information. [Illustration: _Engraved by C. E. Wagstaff._ LORD CLARENDON. _From the Picture in the Bodleian Library, Oxford._ Under the Superintendance of the Society for the Diffusion of Useful Knowledge. _London, Published by Charles Knight, Ludgate Street._ ] [Illustration] CLARENDON.