The feelings of the sanguine philanthropist may be conceived. They cannot be better described than they have been by himself in the following terms. “While the vaccine discovery was progressive, the joy I felt at the prospect before me of being the instrument destined to take away from the world one of its greatest calamities, blended with the fond hope of enjoying independence and domestic peace and happiness, was often so excessive, that in pursuing my favourite subject among the meadows, I have sometimes found myself in a reverie. It is pleasant to me to recollect that these reflections always ended in devout acknowledgments to that Being from whom this and all other mercies flow.” During the next two years many other equally successful trials were made; and at length the discovery was published to the world in June, 1798, in a quarto pamphlet of seventy pages, which had been previously subjected to the most rigorous criticism and revision by a few chosen friends who met for that purpose at the house of Thomas Westfaling, Esq., at Rudhall, near Ross. It is entitled ‘An Inquiry into the Causes and Effects of the Variolæ Vaccinæ; a disease discovered in some of the Western Counties of England, particularly Gloucestershire, and known by the name of the Cow-pox.’ The pamphlet is enriched with the detail of sixteen cases of the casual, and seven of the inoculated disease, the latter including the case of one of the author’s sons; and with coloured drawings of the appearances in both.