Though dealing exactly with a surgical subject, this book is a layman's word to laymen. It is an attempt to say to the general public a few things about this amazing work of Dr. J. R. Brinkley, of Milford, Kansas, which he is debarred from saying for himself in this simple form. He has under consideration a book of his own covering the subject of Goat-Gland Transplantation, his experiments, successes, failures, theories, and conclusions, which will probably be issued during the winter of 1922, and in that book he expects to treat his subject exhaustively with full medical and surgical detail, in a manner acceptable to the medical profession. But, in the meantime, no satisfactory effort has been made to tell the story to the general public, except in the fragmentary form of occasional newspaper notices. The author feels that the chief interest in this matter abides with the patient rather than with the practitioner, or, if not the chief interest, at least an equal interest. It seems proper, therefore, that the subject should be briefly dealt with at this time, while it is yet in its infancy, in such a manner that the general public may grasp the essentials of what is being done in America in this new application of endocrinology. Some attention is paid to the pioneer work of Dr. Frank Lydston of Chicago in the transplanting of human glands into human beings, but rather by way of emphasizing the fact that Dr. Brinkley, with the choice of human, monkey, goat, or sheep glands before him, chose the goat-glands in preference to any other for his field of experiment and operation, and has never for a moment regretted his choice, or seen any reason to alter it.