It is surprising that the affair of Virues, and many others, did not make Charles V. perceive the nature of the Inquisition, and that he still continued to protect that institution. However, the trial of his preacher, and several other crosses which he experienced about that time, were the reasons why he deprived the holy office of the royal jurisdiction in 1535, and it was not restored until the year 1545. This favour for Virues was so constant, that he soon after presented him to the Pope for the bishopric of the Canaries; but the Pope refused him, alleging that the suspicions raised against the purity of his faith rendered him improper to be invested with the dignity of a bishop, although the bull had declared him to be eligible. The emperor insisted, and the Pope at length yielded to his pressing solicitations. Virues was made Bishop of the Canaries in 1540. In 1527 the Inquisition of Valladolid was occupied by an affair, of which it is necessary to give an account, that the compassion and indulgence which the inquisitors always professed in their acts, and other forms of justice, may be justly appreciated. One Diego Vallejo, of the village of Palacios de Meneses, in the diocese of Palencia, having been arrested for blasphemy by the Inquisition, declared, among other things, that two months before, on the 24th of April, 1526, two physicians, named Alphonso Garcia and Juan de Salas, were disputing on the subject of medicine, before him and Ferdinand Ramirez, his son-in-law: the first maintained his opinion on the authority of certain writers; Salas affirmed that these writers were deceived; Garcia replied that his opinion was proved by the text of the evangelists, which caused Salas to say _that they had lied as well as the others_. Ferdinand Ramirez (who had also been arrested upon suspicion of Judaism) was examined the same day; his deposition was the same as that of Vallejo, but he added, that Salas returned to his house some hours after, and in speaking of what had passed, said, "_What folly I have asserted!_" When the tribunal had finished the affair of Ramirez and Vallejo, they arrested Juan de Salas.