"In an excavation made in the corner-stone was deposited a glass bottle enclosing a parchment roll on which were written the name of the President of the United States, those of the heads of departments, the Trustees of Transylvania University, the medical professors, trustees of the town, officers of the Grand Lodge who assisted at the ceremony, building committee, architect, etc. On a marble tablet over the front door of the house is the following inscription: COLL. TRANSYL. MEDIC. FUND. A. D. MDCCCXVII. "Though plain and unostentatious, the style of its architecture is chaste and neat, its execution is solid and substantial, and its interior arrangements are of the most convenient, comfortable, and commodious kind. "The basement story of the building is chiefly appropriated to the chemical professorship and contains a lecture-room forty-five by fifty feet in dimensions, in which the seats and lecturing stand are arranged in the best manner for perfect vision, a lobby, an anti-room, a chemical laboratory well supplied with all necessary apparatus, and a dormitory for a resident pupil who acts as librarian. "These in connection with the very handsome and commodious anatomical amphitheater which was built during the preceding season, together with its preparing- and dissecting-rooms, present a suit of lecture-rooms, apartments, etc., not surpassed in point of excellence of light for demonstration, or in ease, comfort, and convenience to the pupil by any similar institution in America. The whole is situated in a pleasant and central part of the town, easily accessible from the chief boarding-houses in the worst weather."[37][38] From the time of the reorganization in 1819, the classes in the Medical College increased rapidly--from only twenty, with a single graduate in 1817-18, to two hundred students and fifty-six graduates in the session of 1823-24. A rapid increase in patronage almost unparalleled in the history of medical schools, owing, no doubt, largely to the great increasing demand for medical instruction in this fast improving country and to the temporary extreme difficulty of the journey to the great medical school of Philadelphia, but also to the _eclat_ of the University under the administration of Doctor Holley,[39] to the just fame of Doctor Dudley as a surgeon and medical teacher, to the reputation of Doctor Samuel Brown as a popular and cultivated physician and professor, and to the brilliant and popular talents of Doctor Charles Caldwell. DOCTOR CHARLES CALDWELL. The association of this distinguished professor with the fortunes of the Medical Department of Transylvania, which extended from 1819 to 1837, marked the era of its most rapid development, and embraced a large portion of the time of its greatest prosperity.