Doctor Bush was married, in 1835, to Miss Charlotte James, of Chillicothe. Of their three children the eldest, Benjamin Dudley, was a young man of remarkable promise as a surgeon and physician when he was cut off, an event which cast a gloom over the remaining days of the life of his father. Few young men of his age had ever attained such proficiency or developed such sterling qualities.[87] The death of Doctor Bush, which took place on February 14, 1875, was followed by general and unusual manifestations of respect and regret, not only on the part of the members of the profession, but by the people of the city at large. Few citizens were more extensively known, loved, and honored in life or followed to the grave by a greater concourse of mourning friends. NATHAN RYNO SMITH, M. D., Was called from his residence in Baltimore, Maryland, to the chair of Theory and Practice of Medicine in Transylvania in the year 1838. He resigned the chair and returned to that city in 1840, having delivered three annual courses of lectures here. He was succeeded in this chair by Doctor Elisha Bartlett. Doctor Smith was born May 21, 1797, in the town of Cornish, New Hampshire, where his father, Nathan Smith--afterward Professor of Physic and Surgery in Yale College--had been for ten years in the practice of his profession. In a brief sketch of his father, Doctor Smith unconsciously drew the outlines of his own character. "In the practice of surgery," he said, "Professor Smith displayed an original and inventive mind. His friends claim for him the establishment of scientific principles and the invention of resources in practice which will stand as lasting monuments of a mind fertile in expedients and unshackled by the dogmas of the schools." The father, at the age of twenty-four, after an early life of industry and adventure in the then new country, had been so impressed and attracted by witnessing a surgical operation that he at once devoted himself to surgery and medicine, and with such ardor and success that for forty years succeeding he was a distinguished member and teacher in his profession. The son, with much the same natural bent of mind, after receiving his early education at Dartmouth and graduating at Yale in 1817--spending a year and a half in Virginia as a classical tutor--began the study of medicine in Yale, where his father was Professor of Physic and Surgery. He there received the degree of Doctor of Medicine, in 1823. He began practice in Burlington, Vermont, in 1824. In 1825, he was appointed Professor of Surgery and Anatomy in the University of Vermont, the Medical Department of which was organized principally by his exertions, aided by his father.