The Hospital Bulletin, Vol. V, No. 3, May 15, 1909Various
History
The Hospital Bulletin, Vol. V, No. 3, May 15, 1909
Various
Medical colleges -- Alumni and alumnae -- Maryland -- Baltimore -- Periodicals; Medicine -- Periodicals
“Just one more idea and I shall have finished. It concerns the
demonstration of such research work in places at a distance from the
experimentor's laboratory. Such demonstrations are always attended with
great difficulty. They usually require four animals, two or three
janitors to transport them, and as many laboratory assistants as the
director of the laboratory can manage to take with him. The technique of
these operations, the high-grade sensitiveness of operated animals, the
refinement with which chemical tests should be made, all require for
their safe conduct that the experimentor should work only with those men
who are used to his system. The animals themselves are always influenced
in one way or other by the presence of strangers. I remember in one
animal which was demonstrated on March 17th, at the University Hospital,
the demonstration at which Dr. Satterthwaite was present, a most
unexpected change in the quality of the gastric secretions took place.
This was a control animal which had undergone no operation whatever. He
was simply taken along to show the proteolytic power of a normal dog and
compare it with the operated dogs. His gastric juice had been previously
tested on several occasions, and always found to be of regular standard,
but on the night of the demonstration before the Medical Society this
animal's gastric juice was practically inactive, containing no HCL nor
pepsin.
“Dr. Hemmeter has already informed you that in some animals the loss of
gastric juice after extirpation of the salivary glands is only
temporary, and that in varying time—in some cases three weeks, in other
animals three to four months—there is a gradual resumption of gastric
secretion. This resumed secretion, however, never becomes as effective
as it was in the same dog before an operation. The question when to
begin to make observations on an operated animal depends entirely upon
the state of this animal; if the dog eats his food with appetite, he has
no fever, and his digestion appears to be satisfactory; then the
observations may be begun, even if it is only one week or ten days after
the last operation. One of the most valuable animals that was used in
this series of experiments was so injured in the effort to transport him
to another laboratory that he could not be used for further
experimentation. The dog struggled so in his holder while he was being
transported in a wagon that the partition of true mucosa which separates
the accessory from the plain stomach was broken through. This had
happened once before in transporting a dog from the laboratory to Dr.
Hemmeter's country place, and his associates in the Medical Faculty,
becoming aware of the great labor and cost involved in such operations,
and the rarity with which they succeed, advised that no further Pawlow
dogs be sent to other laboratories.”
AN INTERESTING CASE OF SCROTAL HERNIA.
BY G. E. BENNETT, '09.
Public-domain text, read in full here on John Shaqi.
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