It was soon realized by the missionaries that but meagre results could be obtained until the Indians were induced to lead a sedentary life. Their wandering habit nullified all attempts at permanent instruction to the young; it engendered improvidence and laziness, bred famine and disease; and the constant struggle to kill fur-bearing animals for their pelts rapidly depleted the game, while the fur trade wrought contamination in many forms. Missionary efforts were at first conducive to the interests of the fur trade, by bringing far-distant tribes within the sphere of French influence; but so soon as the Jesuit sought to change the habits of the natives, to cause them to become agriculturists instead of hunters, and to oppose the rum traffic among them, then the grasping commercial monopoly which controlled the fortunes of New France, and was merely "working" the colony for financial gains, saw in the Jesuit an enemy, and often placed serious obstacles in his path. In pursuance of the sedentary policy, and also to protect the wretched Montagnais from Iroquois war-parties, the Jesuits, in 1637, established for them a palisaded mission four miles above Quebec, at first giving it the name St. Joseph, but later that of Sillery, in honor of Commander Noël Brulart de Sillery, of France, who had given ample funds for the founding of this enterprise. Here were at first gathered twenty of the Indians, who began cultivation of the soil, varied by occasional hunting and fishing trips, which the missionaries could not prevent. The little town slowly grew in importance, both Algonkins and Montagnais being represented in its population. Three years later, nuns opened a hospital at Sillery, for the reception of both French and Indian patients, and thus greatly added to the popularity of the mission. But in 1646 the nuns removed their hospital to Quebec; a few years later, the church and mission house were destroyed by fire; disease made sad havoc in the settlement; the thin soil became exhausted through careless tillage; Iroquois preyed upon the converts, until at last the Algonkins almost entirely disappeared; and although their place was taken by Abenakis from Maine and Acadia, until the attendance became almost solely Abenaki, the enterprise waned. In 1685, it was abandoned in favor of St. Francis de Sales, a new mission established at the falls of the Chaudière River, not far from the St. Lawrence. Beyond a monument of later days, to the memory of Fathers Massé and De Nouë, whose names are prominently connected with this work, nothing now remains to mark the site of the old Sillery mission.