Examination revealed a large pharyngeal ulcer on the left side, with enlarged cervical glands on the same side, and my suspicions were aroused as to its malignancy. Upon expressing such a fear the patient admitted that she had been examined by a surgeon who likewise had suspected carcinoma and advised its removal. She absolutely refused to think of operation at anybody’s hands, and insisted upon my giving it the best treatment possible. I cleansed it with the usual antiseptic solutions, and applied orthoform and other well-known and everyday methods for a week or two with a fair amount of relief, but the ulcer continuing, I applied specific treatment in the hope of clearing up the diagnosis, and, much to my delight as well as to the patient’s comfort, the ulcer healed, the induration disappeared and the patient was, to all intents and purposes, well. After a number of weeks the external glands even diminished in size, so that I rather felt that the diagnosis of cancer was wrong and that it must be specific in character. The patient ceased her visits, but returned in a few more weeks with a condition as at first, but upon the opposite side of the pharynx. Same treatment and everything else I could suggest did absolutely nothing for her relief, and I felt that the diagnosis this time must be carcinoma, but she refused even to have a small section taken for the purpose of diagnosis. Consultation agreed with me as to the malignancy of the growth, but operation was refused. She died in another month, practically from starvation. I report this case after having read the article by A. Worrall Palmer upon cancer of the larynx, in the January number of this journal, because in the prelude, this method of diagnosis, and the application of this specific mixed treatment is advised, and because in this case it was followed by apparently successful results with what seemed to be an entire cure of the case, and therefore a clearing up of the diagnosis, but which, on the other hand, was followed by a return of the same condition, but upon the other side of the throat. The second point in the case is the great relief of all symptoms following the iodide of potash and merc. administered internally, and the administration of kali bi. and arsen., which most certainly had in the early part of the disease a very satisfactory effect. I believe that this case was cancer from the first, but that, contrary to expectations, it yielded beautifully to internal treatment.