_Persons afflicted living in the interior, can, by stating fully in a letter their symptoms, receive advice and remedies at home._ =Important to Persons Afflicted with Venereal=. There are no maladies, either in a medical or moral point of view, worse than those arising from the contamination of VENEREAL POISON. None are more terrible in their effects, or more disastrous in their results. MERCURY will not cure VENEREAL, BUT DRIES ON THE SURFACE, TO ALLOW IT TO POISON AND DESTROY THE BLOOD, TO RE-APPEAR IN HIDEOUS MARKS UPON THE BODY, and in the throat, mouth and nose. Having treated a great number of nautical men, the Doctor fully understands their peculiar requirements, and the medicines prescribed do not interfere with their occupation. All letters should be addressed, Dr. BENJ. F. JOSSELYN, M. D. 618 Sacramento street, between Montgomery and Kearny, San Francisco. Box 735. =AMERICAN AND FOREIGN PATENT AGENTS=. Mining and Scientific Press. =PUBLISHED EVERY SATURDAY=, At No. 414 Clay Street, San Francisco. If you are an Inventor, Patentee, Miner, Farmer, Manufacturer, Mechanic, or a progressive Student or Artisan in any Industrial or Professional Calling in the Pacific States or Territories, you are doing yourself irreparable injustice, if not already a subscriber and reader of the MINING AND SCIENTIFIC PRESS. It contains hints and information enough to repay the subscription price many times in a single month. Its columns are filled with instructive reading in plain, comprehensible and attractive form to minds of ordinary intelligence. It contains 16 pages and 64 columns of the size of Harpers’s Weekly, and is the best printed and most valuable paper on the western half of the continent. All claims of patents issued to inventors on this coast are reported. Illustrations of new machinery are given each week. Descriptions of new inventions and discoveries throughout the world, are given, with fresh and comprehensive information of scientific developments and mechanical and industrial progress, which cannot be obtained from books, or readily found gathered in so convenient a form elsewhere. Subscribe now, and you will not regret it. =PATENT AGENCY=.