(i.) "The occult premonitory signs of Leprosy are, a reddish colour of the face, verging to duskiness; the expiration begins to be changed, the voice grows hoarse, the hairs become thinned and weaker, and the perspiration and breath incline to foetidity; the mind is melancholic with frightful dreams and nightmare; in some cases scabs, pustules, and eruptions break out over the whole body; disposition of the body begins to become loathsome, but still, while the form and figure are not corrupted, the patient is not to be adjudged for separation; but is to be most strictly watched." (ii.) "The infallible signs, are, enlargement of the eyebrows, with loss of their hair; rotundity of the eyes; swelling of the nostrils externally, and contraction of them within; voice nasal; colour of the face glossy, verging to a darkish hue; aspect of the face terrible, and with a fixed look; with acumination or pointing and contraction of the pulps of the ear. And there are many other signs, as pustules and excrescences, atrophy of the muscles, and particularly of those between the thumb and forefinger; insensibility of the extremities; fissures, and infections of the skin; the blood, when drawn and washed, containing black, earthy, rough, sandy matter. The above are those evident and manifest signs, which, when they do appear, the patient ought to be separated from the people, or, in other words, secluded in a Lazar House." (iii.) "The signs of the last stage and breaking-up of the disease, are, corrosion and falling-in of the cartilage forming the septum of the nose; fissure and division of the feet and hands; enlargement of the lips, and a disposition to glandular swelling; dyspnoea and difficulty of breathing; the voice hoarse and barking; the aspect of the face frightful, and of a dark colour; the pulse small, almost imperceptible." Sometimes the limbs drop off, piecemeal or in their entirety. All the writers agree in urging most earnestly that no one ought to be adjudged a Leper, unless there manifestly appears a corruption of the figure, or, that state indicated as _signa infallibilia_. LAZAR HOUSES. The period from its introduction into this country, as far as we know, to its final or nearly final extinction, may be embraced within the 10th and 16th centuries. It was at the zenith of its height during the 11th, 12th, and 13th centuries. As early as A.D. 948 laws were enacted with regard to Lepers in Wales by Howel Dda, the Good--the great Welsh King, who died 948. The enormous extent to which it prevailed during that period may be gauged from the fact, that there were above 200 Lazar Houses in England alone, probably providing accommodation for 4,000 at least, and this, at a time when the whole population of England was only between 2,000,000 and 3,000,000 of persons; being something like two in every thousand.