Early in 1866 a double opportunity seemed to offer itself to Miss Nightingale for advancing her cause. At the beginning of February Sir Charles Wood resigned office, and her friend, Lord de Grey, became Secretary of State for India in his place. At the same time she had received an important letter from the Governor-General (dated Calcutta, Jan. 19). Her friend, Mr. Ellis, who had been in conclave (as we have heard) with her and her circle, had shortly before submitted proposals to him. Sir John Lawrence wrote to her: "As regards the reconstruction of our sanitary organizations, we are sending home to the Secretary of State a copy of Mr. Ellis's note which he sent me, and are proposing a further change somewhat in accordance with his plan. I have no doubt that you will see the dispatch, and therefore I had better not send it to you." He then went on to give a summary of its contents. The summary was brief, and allowed of different opinions as to the ultimate bearing of the Governor-General's proposals. He had assumed as a matter of course that she would be shown his dispatch, and she applied to her official friends for a sight of it. They would be delighted if they had it, but they had received no such dispatch; perhaps it would come by the next mail. But it did not, nor by the next, nor the next, for a very simple reason, as will presently appear. Miss Nightingale put on her friend Mr. Ellis, who as the head of a Presidency Health Commission had a direct _locus standi_, to inquire and even to search at the India Office. "They swear by their gods," he reported, "that they have no such dispatch." Miss Nightingale was becoming desperate. She was perfectly certain that Sir John Lawrence must have sent it. Meanwhile the Home Government was tottering to its fall; the new Secretary of State might be one who knew not Miss Nightingale. She entreated that a further search should be made. On May 5 she was told that "at last the Sanitary Minute had been found, and a copy of it was sent for her consideration. It had been attached to some papers connected with the Financial Department and thus had escaped attention. Lord de Grey begged Miss Nightingale to let him have the benefit of her opinion upon it as soon as possible." She afterwards learnt that it was the Secretary of State himself who, with his own hands, had searched for and found the Governor-General's Minute. It had "escaped attention" for nearly four months. The incident did not raise Miss Nightingale's opinion of government offices, or lessen her sense of responsibility in the duty of keeping the sanitary question to the fore. She was ill when the Minister's message arrived; but she at once set to work, and on May 7 she sent in a memorandum giving a summary of her views, and pointing out wherein the Governor-General's proposals seemed to require revision if the recommendations of the Royal Commission were to be carried out effectually. The Minister was busy with many things. His own fate and