The charity and fortitude of the Mothers was very soon put to a severe test. Towards the end of August, the small-pox broke out among the savages, with whom it is usually fatal. After spreading with frightful rapidity through the hamlet of Sillery, it showed itself at the Ursuline Convent in Quebec, which was soon transformed into an hospital. Some of the children contracted the disease three different times, and four died of it. Through the protection of heaven, their devoted nurses escaped under circumstances which rendered their preservation almost miraculous. Night and day they watched their beloved patients, inhaling only the plague-tainted air of the small, overcrowded room, and having continually to step across the infected beds, which for want of space were laid closely together along the floor. During the six months which the malady lasted, these heroines of charity seemed to vie with each other in the performance of the most bumbling and revolting offices, the Foundress setting the example of self-abnegation and devotedness. Their sole apprehension all through, was lest the panic-stricken savages might remove their children from the monastery, and thus deprive them of the spiritual blessings in store, an idea being prevalent among the unconverted Indians, that the small-pox was a consequence of receiving baptism, and of associating with the French. Fortunately the fear proved groundless, for the little ones were afterwards confided in larger numbers than ever, to the care of their tender, self-sacrificing Ursuline mothers. When at last the contagion disappeared, the wardrobe of the charitable Sisters was found not to have been the least of the sufferers in the cause, every available article of clothing having been converted into bandages for the sores of the poor patients. The accounts from Canada might naturally have been expected rather to check than to encourage vocations for the Ursuline mission, but on the contrary, each letter from the Mother of the Incarnation to her Sisters of Paris and Tours, served only to stimulate a holy emulation to share in her sacrifices. "To enter," she says, "into the true spirit of a missioner to Canada, the soul must die to all things created; on this point, the Almighty Master is inexorable. Interior death is no doubt the sure road to life in God, but who can describe what it costs nature thus to die!" Notwithstanding the Venerable Mother's forewarnings, the Mother Superior of the Paris convent prevailed on the Archbishop to allow two of the Sisters to follow their call to Canada. The privileged two were the Mother St. Athanasius and St. Clare, who in the world had borne the names of Margaret de Flécelles and Anne le Bugle. On the 7th of July, 1640, they landed at Quebec to the great joy of their expectant Sisters. This addition to the original number necessitated the immediate building of a monastery, which want of means had hitherto retarded.