During her stay at Adrianople she discovered something better, however, than Turkish illustrations of Homer, for it was here that she first observed the practice of inoculation for the small-pox, which she had the hardihood to try upon her own children, and was the first to introduce it into England. Among the Turks, who, in all probability, were not its inventors, it was termed _ingrafting_, and the whole economy of the thing, according to the invariable policy of barbarians, was intrusted to the management of old women. Upon the return of the embassy to England, a Mr. Maitland, the ambassador’s physician, endeavoured, under the patronage of Lady Montague, who ardently desired its extension, to introduce the practice in London; and in 1721, the public attention having been strongly directed to the subject, and the curiosity of professional men awakened, an experiment, sanctioned by the College of Physicians, and authorized by government, was made upon five condemned criminals. With four of these the trial perfectly succeeded, and the fifth, a woman, upon whom no effect was produced, afterward confessed that she had had the small-pox while an infant. The merit of this action of Lady Montague can scarcely be overrated, as, by exciting curiosity and inquiry, it seems unquestionably to have led the way to the discovery of vaccination, that great preservative of life and beauty, and produced at the time immense positive good.[4] Footnote 4: A writer in the Annual Register for 1762, thus calculates the amount of the benefit conferred on the British public by Lady Montague:—“If one person in _seven_ die of the small-pox in the natural way, and one in _three hundred and twelve_ by inoculation, as proved at the small-pox hospital, then, as 1,000,000 divided by seven, gives 142,857½, 1,000,000 divided by 312, gives 3,205 46-312. The lives saved in 1,000,000 by inoculation must be 139,652 11-31. In Lord Petre’s family, 18 individuals died of the small-pox in 27 years. The present generation, who have enjoyed all the advantages of inoculation, are adequate judges of the extremely fatal prevalence of the original disease, and of their consequently great obligations to Lady Mary Wortley Montague.”—Sir Richard Steele, in the Plain Dealer, prefers the introduction of this practice to all “those wide endowments and deep foundations of public charity which have made most noise in the world.”