An illustration of the effects of the lack of sensory stimuli on the cortex is well shown in the case of Laura Bridgman, whose brain was studied by Professor Donaldson after her death. Laura Bridgman was born a normal child, and developed as other children do up to the age of nearly three years. At this time, through an attack of scarlet fever, she lost her hearing completely and also the sight of her left eye. Her right eye was so badly affected that she could see but little; and it, too, became entirely blind when she was eight. She lived in this condition until she was sixty years old, when she died. Professor Donaldson submitted the cortex of her brain to a most careful examination, also comparing the corresponding areas on the two hemispheres with each other. He found that as a whole the cortex was thinner than in the case of normal individuals. He found also that the cortical area connected with the left eye--namely, the right occipital region--was much thinner than that for the right eye, which had retained its sight longer than the other. He says: "It is interesting to notice that those parts of the cortex which, according to the current view, were associated with the defective sense organs were also particularly thin. The cause of this thinness was found to be due, at least in part, to the small size of the nerve cells there present. Not only were the large and medium-sized cells smaller, but the impression made on the observer was that they were also less numerous than in the normal cortex." EFFECT OF SENSORY STIMULI.--No doubt if we could examine the brain of a person who has grown up in an environment rich in stimuli to the eye, where nature, earth, and sky have presented a changing panorama of color and form to attract the eye; where all the sounds of nature, from the chirp of the insect to the roar of the waves and the murmur of the breeze, and from the softest tones of the voice to the mightiest sweep of the great orchestra, have challenged the ear; where many and varied odors and perfumes have assailed the nostrils; where a great range of tastes have tempted the palate; where many varieties of touch and temperature sensations have been experienced--no doubt if we could examine such a brain we should find the sensory areas of the cortex excelling in thickness because its cells were well developed and full sized from the currents which had been pouring into them from the outside world. On the other hand, if we could examine a cortex which had lacked any one of these stimuli, we should find some area in it undeveloped because of this deficiency. Its owner therefore possesses but the fraction of a brain, and would in a corresponding degree find his mind incomplete.