I could now go into the rooms of the sick with a formula that explained all the mysteries of the maintenance and support of vital power and cure of disease, and that was of practical avail. I now knew that there could be no death from starvation until the body was reduced to the skeleton condition; that therefore for structural integrity, for functional clearness, the brain has no need of food when disease has abolished the desire for it. Is there any other way to explain the power to make wills with whispering lips in the very hour of death, even in the last moments of life, that the law recognizes as valid? I could now know that to die of starvation is a matter not of days, but of weeks and months; certainly a period far beyond the average time of recovery from acute disease. III. There fell to my care a very much worn-out mother, who took to her bed with an attack of inflammatory rheumatism, with the joints so involved as to require the handling of a trained nurse. The agony was such that the hypodermic needle was required to make existence endurable, and it was used with the idea that the brain would be less injured by the remedy than by the agony with its inevitable loss of sleep. I know of no disease in which treatment has been more savage than in this. The remedies in common use at that time were mainly new and of supposed specific powers; but they were so violent, and proved to be so futile, that they have all been given up since by the majority of the profession. As the days went on the disease declined in spite of the enforced comfort through the needle; there were easier movements, a clearing of the skin from sallow to a tint of redness, and finally, after a month, the armchair could be used for a change. On the morning of the forty-sixth day there was revealed in the face the perfect color of health, and happiness marked every line of the expression. There was ability to walk through several rooms of her home. But it was not until the afternoon that the first food was desired and taken, and never before was plain bread and butter, the supreme objects of desire, so relished. In the following few months there was an actual gain of forty pounds. My next marked case is a wonderful illustration of the self-feeding power of the brain to meet an emergency, and a revelation, also, of the possible limitations of the starvation period. This was the case of a frail, spare boy of four years, whose stomach was so disorganized by a drink of solution of caustic potash that not even a swallow of water could be retained. He died on the seventy-fifth day of his fast, with the mind clear to the last hour, and with apparently nothing of the body left but bones, ligaments, and a thin skin; and yet the brain had lost neither weight nor functional clearness. In another city a similar accident happened to a child of about the same age, in whom it took three months for the brain to exhaust entirely the available body-food.