During the next week the animal grew steadily worse, and would eat only when coaxed with a little milk or with bread softened with milk, the diet of bread and lard being invariably refused. There was marked disturbance of the gastro-intestinal tract; bloody discharges were frequent; the mucous membrane of the mouth was greatly inflamed and very sore; body-weight fell off, and the animal was in a very enfeebled condition. This continued until December 4, with every indication that the animal would not long survive, but by feeding carefully with a little milk and occasionally some meat, improvement finally manifested itself, and by December 18 there was good appetite, provided bread was not conspicuous in the food. Body-weight, which had fallen to 15.5 kilos, was being slowly regained, and on December 30 the animal was again placed on a weighed diet, consisting of 70 grams of meat, 442 grams of milk, 210 grams of cracker dust, and 10 grams of lard. This diet contained 8.26 grams of nitrogen and had a fuel value of 1330 calories, equivalent to 0.5 gram nitrogen and 80 calories per kilogram of body-weight. On January 12, 1906, the weight of the animal was 16.7 kilos, while in general condition there was nothing to be desired. The food was then modified by diminishing the amounts of meat and milk fed daily by one-half, thus reducing the nitrogen intake to 0.35 gram per kilo of body-weight, but maintaining the fuel value of the food at 80 calories per kilo. Under this régime, body-weight still increased, and on January 27 was 17.5 kilograms. A balance period, shown in the accompanying table, extending from January 30 to February 8, affords ample evidence that the body was laying by nitrogen. SUBJECT No. 17. DAILY AVERAGES