In addition to these hopeful indications in encouragement of a vigorous effort to abandon the habit, there were on the other hand certain warnings which could not safely be neglected. The stomach began to complain,--as well it might after so many years unnatural service,--that the daily task of disposing of a large mass of noxious matter constantly cumulating its deadly assaults upon the natural processes of life was getting to be beyond its powers. The pulse had become increasingly languid, while the aversion to labor of any kind seemed to be settling down into a chronic and hopeless infirmity. Some circumstances connected with my own situation pointed also to the appropriateness of the present time for an effort which I knew by the experience of others would make a heavy demand upon all one's fortitude, even when these circumstances were most propitious. At this period my time was wholly at my own disposal. My family was a small one, and I was sure of every accessory support I might need from them to tide me over what I hoped would prove only a temporary, though it might be a severe, struggle. The house I occupied was fortunately so situated that no outcry of pain, nor any extorted eccentricity of conduct, consequent upon the effort I proposed to make, could be observed by neighbors or by-passers. A few days before the task was commenced, and while on a visit to the capital of a neighboring State in company with a party of gentlemen from Baltimore, I had ventured upon reducing by one-quarter the customary daily allowance of eighty grains. Under the excitement of such an occasion I continued the experiment for a second day with no other perceptible effect than a restless indisposition to remain long in the same position. This, however, was a mere experiment, a prelude to the determined struggle I was resolved upon making, and to which I had been incited chiefly through the encouragement suggested by the success of De Quincey. There is a page in the "Confessions" of this author which I have no doubt has, been perused with intense interest by hundreds of opium-eaters. It is the page which gives in a tabular form the gradual progress he made in diminishing the daily quantity of laudanum to which he had long been accustomed. I had read and re-read with great care all that he had seen fit to record respecting his own triumph over the habit. I knew that he had made use of opium irregularly and at considerable intervals from the year 1804 to 1812, and that during this time opium had not become a daily necessity; that in the year 1813 he had become a confirmed opium-eater, "of whom to ask whether on any particular day he had or had not taken opium, would be to ask whether his lungs had performed respiration, or the heart fulfilled its functions;" that in the year 1821 he had published his "Confessions," in which, while leading the unobservant reader to think that he had mastered the habit, he had in truth only so far succeeded