account any bad effect of the heat might be the more unmitigated. Another symptom, viz., what in my ignorance I call internal rheumatism (sometimes affecting the shoulders, etc., but more often appearing to be seated in the stomach), seemed again less probably attributable to the opium or the want of opium than to the dampness of the house which I inhabit, which had about that time attained its maximum, July having been as usual a month of incessant rain in our most rainy part of England. Under these reasons for doubting whether opium had any connection with the latter stage of my bodily wretchedness--except indeed as an occasional cause, as having left the body weaker and more crazy, and thus predisposed to any mal-influence whatever--I willingly spare my reader all description of it. Let it perish to him; and would that I could as easily say, let it perish to my own remembrances, that any future hours of tranquillity may not be disturbed by too vivid an ideal of possible human misery! So much for the sequel of my experiment As to the former stage, in which properly lies the experiment and its application to other cases, I must request my reader not to forget the reason for which I have recorded it. This was a belief that I might add some trifle to the history of opium as a medical agent. In this I am aware that I have not at all fulfilled my own intentions, in consequence of the torpor of mind, pain of body, and extreme disgust to the subject which besieged me while writing that part of my paper; which part being immediately sent off to the press (distant about five degrees of latitude), can not be corrected or improved. But from this account, rambling as it may be, it is evident that thus much of benefit may arise to the persons most interested in such a history of opium--viz., to opium-eaters in general--that it establishes for their consolation and encouragement the fact that opium may be renounced without greater sufferings than an ordinary resolution may support, and by a pretty rapid course of descent. On which last notice I would remark that mine was _too_ rapid, and the suffering therefore needlessly aggravated; or rather perhaps it was not sufficiently continuous and equably graduated. But that the reader may judge for himself, and above all that the opium-eater who is preparing to retire from business may have every sort of information before him, I subjoin my diary. FIRST WEEK Drops of Laud. Monday, June 24....... 130 Tuesday, " 25....... 140 Wednesday, " 26....... 130 Thursday, " 27....... 80 Friday, " 28....... 80 Saturday, " 29....... 80 Sunday, " 30....... 80