_Psychic state_: exceedingly variable, varying culturally, with the stages of intoxication, and in the individual himself at different times. Mexican visions sometimes have a frightening tone, sometimes one of hilarity. The writer had marked confirmation of this while still ignorant of this ethnographic fact: in an Oto meeting in 1936 visions were of monstrous animals so ridiculous and hilariously funny that proper self-restraint in meeting was difficult; yet, in a control experiment comfortably conducted in New Haven, the psychic state developed into one of stark, galloping, psychotic terror, quite inexplicable on realistic grounds (later, parallels were found in Winnebago material and in white observations). Curiously enough Dixon noted in a cat photophobia, dilated pupils and a fixed “stare ... [and] most of the physical elements of ‘terror.’ ... The ears were drawn back, the hair over the body, especially the tail, becomes erected, there is twitching of the superficial muscles, the respiration being shallow and hurried, and the heart weak and irregular.” One experimenter’s subject became possessed of the fixed idea that he was being poisoned, when the intoxication had thoroughly developed. This experience, once felt, is so strikingly physiological that one is tempted to wonder if there is any hypersecretion of adrenalin, perhaps in adjustmental reaction to the effect of the alkaloids on the heart. Dixon thought _Lophophora_ differed from _Cannabis indica_ in never provoking merriment; yet Wertham and Bleuler had one subject who achieved a state of to him quite meaningless hilarity. Fear states are present among native users also, to judge from the content of some visions recorded; conceivably these might be the psychic end-results of the intensified reflex-excitability induced by the strychnine-like alkaloids. However, one should bear in mind throughout the antagonistic effect of the alkaloids, which together with individual, cultural and other differences (physiological state, amount eaten, the form in which the drug is taken—infusion or solid, dry or green—the continued eating of it in late stages of intoxication, etc.) contribute to widely variable reactions. The experiments of Wertham and Bleuler are impressive in this connection.[18] This variability for the same subject at different times, Indians explain, is conditioned by what one starts thinking about when the intoxication begins.[19] PEYOTE AS APHRODISIAC AND ANAPHRODISIAC