To say that a thing exists is to say that it is perceived in some way; that immediately or remotely it affects our state of consciousness. To say that the star Sirius exists is to say that the stimulation of the retina by a minute spot of light transmits certain molecular disturbances along the optic nerve, and that other molecular disturbances are set up in the tissues of the central nervous system. Even if we do not see those dark stars that we know to exist, there are still evidences of their being that in some way affect the instruments of the astronomer and lead to their being perceived. Even if we do not actually see the emanations from a radio-active substance, we can cause these emanations to produce changes in something that we can see. We speak of the star as a minute spot of coloured light. But if we are short-sighted the spot becomes a little flare, and if we are colour-blind the hue of the star is different from what it is to normal persons. If we put a drop of atropine into one eye and then close the other, objects appear to lose their distinctness, but if we close this eye and then open the other, the original sharpness of vision returns. When we are bilious, wisps and spots may appear on a sheet of white paper that at other times was blank. If we take an overdose of quinine, rustlings and singing noises become apparent even in conditions that ought to preclude all sensation of sound. If we have a bad cold, we do not smell substances which at other times strongly affect our olfactory membranes. When we become intoxicated, a host of aberrations of sense displace our normal perceptions of things. Our perception of the universe, therefore, depends on the normal functioning of our organs of sense, that is, such modes of functioning as we can describe and communicate to others, and which are thus common to the majority of other men and women. These perceptions resulting from the normal functioning of the organs of sense constitute givenness, and we enlarge, or conceptualise this givenness and call it the subject matter of science. But what is this reality that we say is external to us? It is, we see, our inner consciousness. If we walk along a road in the dark we can feel what is the nature of the path on which we tread, whether stones or gravel, or sand or grass. But this feeling is obviously not in the soles of our boots, and neither is it in the skin of the feet, for we should feel nothing if the afferent nerves in the legs were severed. Is it then in the brain? It would appear to be there, but it disappears if certain tracts in the brain are injured.