The Past, on which all experience must draw, affords us so little assistance here that it is to the Future we must look for everything. The Present cannot show us in existence any history of Venereal disease as we understand it, but this in no way entitles it to deny the possibility of such a History. Thus it is of the highest importance to make the attempt to arrange and sift the material now ready and accessible, so far as it concerns the Venereal Disease, on principles conformable to the Conception and proper Contents as indicated above of the History of a Disease, and for this a relative completeness of the collected materials suffices. If in this way we are successful in sketching the history of Venereal Disease at any rate in its general outlines, it can quite well be left to the continued efforts of other Investigators to fill in the individual lines of the picture, especially as then and then only is the particular point ascertained by anticipation, at which later accessions must be worked in. In every History, what comes first and foremost is to get to know the original Authorities from which the material for its treatment can be drawn, and this forms the proper Contents of the _Literary_ history of the Disease. Accordingly our first duty will be to give a general survey of the literary helps lying ready to hand for the use of the Historian of Venereal Disease, and at the same time to specify how far these were accessible to ourselves. Thus the reader will be enabled at the very outset to form a judgement as to the completeness of the information supplied; and succeeding Enquirers will learn the gaps that are left remaining for them to fill up. This will conclude a Survey of the historical results so far obtained in connection with the antiquity and time of origin of the Disease; and it will then be possible to indicate the special Scheme we propose to follow in our treatment of the task before us. Abstract of Opinions advanced at various Periods on the question of the Antiquity and First Rise of the Venereal Disease. The different Opinions advanced at various periods on the question of the Antiquity and Origin of the Venereal Disease may at the outset be brought under two main divisions, according as the disease is supposed to have been already known to the Ancients and from their time onwards to have been continuously observed, _or_ on the other hand regarded as having first arisen in the ninetieth year of the XVth. Century. Both views were framed much about the same time, and depended largely on the position and education of the person delivering judgement. The former may be styled the view of the learned, the latter the popular view, though indeed at their first inception it was not so much scientific reasons in either case as men’s prejudices that formed their basis.