At the small village of Uudhera, of the Baroda feudatory state, where plague broke out, inoculation was applied to a half of each family, the other half remaining uninoculated. After that there were twenty-seven cases and twenty-six deaths among sixty-four uninoculated, and eight cases, with three deaths, among seventy-one inoculated of the same households, the proportionate difference in mortality being over eighty-nine per cent. There followed observations on a far larger scale, demonstrating that the mortality of the inoculated, compared to that of the non-inoculated, was on an average between eighty and ninety per cent less. Sometimes this reduction reached ninety per cent. In the Punjaub, in a village called Bunga, there occurred, in two hundred and eighty-one not inoculated, ninety-seven cases of plague and sixty-five deaths, while among seventy-four inoculated there were six cases, but no deaths. In Bangalore, among 80,285 of the inhabitants not inoculated, there were 2,208 deaths from plague, while among 23,537 inoculated there were only 108. The observations at Lanowli, Kirkee, Daman, Hubli, Dharwar, Gadag, in the Bombay Presidency, gave the same results. At Hubli over forty-two thousand inhabitants out of some fifty thousand were inoculated. In Bombay city, out of a population of 821,764, 157,256 have now undergone the inoculation. The work proceeds here at present at the rate of one thousand to eleven hundred inoculations a day. From plague hospitals the returns show that among those of the attacked who were previously inoculated the mortality is reduced to less than one half of that among patients who were not inoculated. The property of reducing the case mortality thus appears to belong to the plague prophylactic in an unmistakable degree. * * * * *