The Present Method of Inoculating for the Small-Pox: To which are added, some experiments, instituted with a view to discover the effects of a similar treatment in the natural small-poxDimsdale, Thomas
History
The Present Method of Inoculating for the Small-Pox: To which are added, some experiments, instituted with a view to discover the effects of a similar treatment in the natural small-pox
Dimsdale, Thomas
Smallpox -- Vaccination -- Early works to 1800
I have been called also to others at the time of eruption, where some
pustules having already appeared, made the matter clear; and in every
case of this kind, I have endeavoured to get the sick person into the
open air, have generally given the mercurial and antimonial pill,
and directed a laxative to be taken some hours after it, in order to
procure three or four stools; and this method I have more particularly
enjoined, and sometimes repeated, where the kind has appeared to be
bad, and where little or no relief has been found from the partial
eruption; the symptoms continuing to be such as portended great danger.
I have followed the same method during every part of the eruptive
fever, intending thereby to abate its violence, to check the eruption,
and prevent the conflux, and consequently the danger[6].
[6] See Cases XXV. XXVI. XXVII. XXIX.
The success attending this practice has hitherto exceeded my
expectations; though it must be confessed, that as the symptoms run
much higher in the natural, than they are found to do in the inoculated
disease, the relief has not been so considerable; and I have found
it extremely difficult to persuade such whose complaints have been
very severe, to quit their beds, and attempt to go abroad: indeed the
exceeding feeble state they are sometimes in, sufficiently shews that
great resolution is requisite to put this in practice.
Among those who have been treated in this manner under my own care
and inspection, not one has died, and the number amounts to about 40.
Some of the most remarkable cases will be subjoined, which will more
satisfactorily explain the practice, and demonstrate its success.
The immediate sensible effects of going into the open air, are, a very
great abatement of heat upon the whole surface of the skin, which,
though but just before intensely hot, generally in a short time feels
not much warmer than that of a person in health: the pulse, from being
very strong, full, and quick, becomes less hard and full, but continues
quick; and I have sometimes observed it to intermit; which, however
alarming it may seem, is not a dangerous symptom.
The pain in the head is always relieved, but that in the back and loins
does not abate in proportion: and although it costs no little pain and
trouble to persist in moving abroad under such circumstances, attended
for the most part with great lassitude, yet the patients are sensible
of the benefits they receive; and entertaining a good opinion of the
usefulness of the practice, commonly behave with great resolution;
and, what is very encouraging, in general think themselves stronger.
Upon going within doors to rest themselves, the pain in the head grows
worse, but is again relieved as soon as they return into the air.
The effects of the medicines are usually these:
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