=Treatment.=--Danger comes from two sources--_septic intoxication_ and _local phlegmons_ or gangrenous destruction. Each is therefore to be combated. Treatment should consist of isolation. There is _no specific internal treatment_ for this disease. Tincture of iron, which was long vaunted as such, has proved unsatisfactory, and is of benefit only as a supporting measure in a limited class of cases. _Constitutional_ measures should be employed: First, for the purpose of maintaining _free excretion_ by bowels and kidneys; second, for the purpose of _supporting_ and maintaining strength; third, for tonic and _stimulant_ measures in prostrated and debilitated patients; and, fourth, for the purpose of _combating intestinal sepsis or intoxication_ from any other source. The robust patients with this disease need no particular tonic. The aged, the enfeebled, the dissipated, the prostrated individuals, and the confirmed alcoholics are those who need vigorous stimulation, partly by alcohol and quinine, and partly by strychnine, preferably given hypodermically, and by the other diffusible stimulants by which they may be kept alive. Pilocarpine, given subcutaneously and pushed to the physiological limit, has been praised by some. If along with prostration there occur restlessness and delirium, then anodynes and hypnotics are serviceable, and should be administered to meet the indication--morphine hypodermically and any of the agents which produce sleep are now most beneficial. Finally, if there is any drug which can be administered in doses sufficient to saturate the system with an antiseptic which shall at the same time not prove fatal because of toxicity, this is the ideal medicament for constitutional use only. Such a drug is not known, but it will be well to give some near approach to it internally, as by administering corrosive sublimate, salol, naphthalin, or something else of this character in doses as large as can be tolerated. Should patients become violent it may be necessary to resort to _mechanical restraint_--a strait-jacket, a restraining sheet, a camisole, etc. _Nourishment_ must be kept up by the administration of the easily assimilable and predigested foods. _Locally_ the number of remedies that have been resorted to is legion. In a mild case of spontaneous erysipelas--_i. e._, where no infection can be traced--it will sometimes be sufficient to put on a soothing application, like a lead-and-opium wash. It often gives relief to have the part protected from air contact, which may be done by a soothing ointment or by dusting the part with a powder, such as bismuth oleate or subnitrate, zinc oxide, etc., these being rubbed up with powdered starch; or by a film of rubber tissue or of oiled silk. Brewers’ yeast applied on compresses and covered with oiled silk is efficacious.