The Propaganda for Reform in Proprietary Medicines, Vol. 1 of 2Council on Pharmacy and Chemistry (American Medical Association)
Science
The Propaganda for Reform in Proprietary Medicines, Vol. 1 of 2
Council on Pharmacy and Chemistry (American Medical Association)
Patent medicines
Papayans (Bell) made by Bell & Co., Orangeburg, N. Y., is said to
consist of the “digestive principle obtained by our own exclusive
process from the fruit of _Carica papaya_, combined with willow
charcoal, chemically pure sodium bicarbonate and aromatics.” The
following statement appears on the package: “For the treatment of
dyspepsia, flatulence, nausea, vertigo, hyperacidity, palpitation
and other symptoms of indigestion and the vomiting of pregnancy.
Peritonitis, cholera morbus, alcoholism and seasickness.” “Digests
every variety of food, removes every symptom of indigestion, restores
the entire digestive tract to a normal condition.” The dosage is
recommended as follows: “From one to three tablets before meals, or two
hours after eating. In severe cases, three tablets dissolved in hot
water and repeated as necessary.”
A circular which accompanies the package details the therapeutic
virtues of the preparation and contains what purports to be extracts
from medical journals, in which Papayans is recommended.
Examination of specimens purchased in the open market showed them
to contain the following ingredients: Charcoal, sodium bicarbonate,
ginger, saccharin and oil of gaultheria. As the product is said to
contain papain, the presence of enzymes was tested for, with the
result that it was found to possess neither proteolytic nor amylolytic
properties. The results of our examination are in accord with the
results obtained by a member of the Council, who examined the product
independently, and who writes:
“We have made some extended tests with Papayans Bell, and find that
the tablets consist essentially of sodium bicarbonate and charcoal,
with a little flavoring matter. We find no digesting power for starch
or egg albumin. At any rate, no appreciable change follows in the
albumin in three hours, and no conversion to sugar in the same time,
or change of starch to a point where the iodin reaction is weakened.
The product seems to be practically inert.”
It is recommended that Papayans Bell be refused recognition, and that
publication of this report be authorized.
Comment: It will be remembered that two other products of Messrs. Bell
& Company have been discussed in this department: Salacetin (Bell)[61]
and Sal-Codeia (Bell).[62] Salacetin was examined with several
“synthetics” which all turned out to be mere acetanilid mixtures.
Salacetin, advertised as “a combination, with heat, of Salicylic and
Glacial Acetic Acids and Phenylamine” when examined “was found to be a
mixture and to contain the following ingredients approximately in the
proportion given: Acetanilid 43; sodium bicarbonate, 21; and ammonium
carbonate, 20.” Sal-Codeia (Salacetin-Codein) therefore, would be the
same with codein added.
[61] See p. 356.
[62] See p. 357.
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