The Propaganda for Reform in Proprietary Medicines, Vol. 1 of 2Council on Pharmacy and Chemistry (American Medical Association)
Science
The Propaganda for Reform in Proprietary Medicines, Vol. 1 of 2
Council on Pharmacy and Chemistry (American Medical Association)
Patent medicines
+-----------------------------------------+
| WM. S. MERRELL CHEMICAL COMPANY |
| “_DIGESTIVE AROMATIC, 5 GRAINS_” |
| “Pepsin 80 parts |
| “Pancreatin 10 parts |
| “Diastase 1 part |
| “Acid Lactic 1 part |
| “Acid Hydrochloric 3 parts |
| “Aromatic Powder 5 parts” |
+-----------------------------------------+
Calculation shows that each tablet should contain about 0.0031 gm. of
absolute hydrochloric acid. The analysis indicated that each tablet
contains about 0.0030 gm. hydrochloric acid (absolute HCl) in protein
combination, or practically the amount claimed. One pharmacopeial dose
of hydrochloric acid is contained in 35 of the tablets.
+-----------------------------------------+
| PARKE, DAVIS & COMPANY |
| “_DIGESTIVE AROMATIC_” |
| “Saccharated Pepsin 4 grains |
| “Pure Pancreatin 1 grain |
| “Diastase 1/4 grain |
| “Aromatic Powder 1/4 grain |
| “Lactic Acid. |
| “Hydrochloric Acid. |
| “Dose: 1 to 3 tablets.” |
+-----------------------------------------+
Chlorid is present in small amounts, but quantitative examination
indicated that hydrochloric acid, either free or in protein combination
is absent. An ammonium salt is present in small quantities.
+-----------------------------------------+
| SHARP & DOHME |
| “_DIGESTIVE AROMATIC_” |
| “Pepsin, Sacch., U. S. P. 4 grains |
| “Pancreatin, pure 1 grain |
| “Diastase 1/4 grain |
| “Aromatic Powder 1/4 grain |
| “Lactic Acid q. s. |
| “Hydrochloric Acid q. s.” |
+-----------------------------------------+
Small quantities of chlorid are present. Quantitative examination
indicated that hydrochloric acid in protein combination is present only
in very small amounts, each tablet containing but about 0.00034 gm.
of absolute acid, or about 0.34 per cent. of the pharmacopeial dose.
Ammonia is absent. Inasmuch as more than 300 of these tablets would be
required to furnish a pharmacopeial dose of hydrochloric acid, this
firm’s interpretation of the expression “q. s.” would prove interesting.
+-----------------------------------------+
| TRUAX, GREENE & COMPANY |
| “_SYNERGIA_” |
+-----------------------------------------+
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