From the preceding investigation, it is concluded that (1) practically there is no difference between the non-proprietary brands of “theobromin sodium salicylate” and “Diuretin;” (2) the several specimens examined were not simple mixtures of “theobromin” and “sodium salicylate”; (3) essentially all the brands complied with the standards laid down and can be rated as satisfactory; (4) “Diuretin,” though sold at an exorbitant price, is not superior to the product supplied under the descriptive term “theobromin sodium salicylate,” and (5) “Diuretin” sells wholesale for $1.75 an ounce, against 35 cents for the “theobromin sodium salicylate,” and therefore its employment cannot be interpreted otherwise than as a useless and unnecessary expense.--(_From The Journal A. M. A., April 4, 1914._) UNGUENTINE W. A. Puckner and A. H. Clark Attention has been called at various times to the fact that the value of a published “formula” to a proprietary remedy is in direct ratio to the reliability of the manufacturer publishing it. When medical journals first insisted on their advertisers letting physicians know the contents of the remedies they wished to sell them, medical literature reeked with formulas--some of them of weird and wonderful design. Since the advent of the Food and Drugs Act, which requires that labels shall approximate truthfulness, and particularly since the Council on Pharmacy and Chemistry has investigated a number of proprietary remedies, the publication of “formulas” is not so common. Unguentine, manufactured by the Norwich Pharmacal Co., is one of those remedies whose advertisement for years always included “a formula”; more recently, however, this is not in evidence. In an advertisement which appeared about ten years ago, the “formula” given is: “Carbolic acid 2 per cent. “Ichthyol 5 per cent. “Alum 15 to 16 per cent.” It was claimed that, by a special process of their own, the manufacturers had eliminated most of the astringent properties of the alum, rendering it non-irritant. It was also stated that “the base of Unguentine is pure petrolatum.” Later the manufacturers seem to have changed the composition of their product, or at least the “formula” given in the advertisements was changed. Thus it appeared: “Alum 15 per cent. “Zinc oxid 5 per cent. “Carbolic acid 2 per cent. “Ichthyol 5 per cent. “Aromatics and antiseptic oils with specially prepared petrolatum and animal fat base.”