In June, 1912, further consideration of Dioradin was requested. The American agent having promised a reform in the methods of advertising, the Council considered the available evidence regarding the identity and value of the preparation. Examination of evidence regarding the composition of Dioradin--claimed to consist of radium chlorid, iodoform and menthol in an ether-oil solution--showed serious discrepancies as to the amount of radium as well as to the identity and amounts of other constituents. It was further found that the experimental evidence was insufficient and biased. Then, too, in view of the difficulty of judging the effects of medicines in tuberculosis, the clinical data were unconvincing. There was nothing to prove that the reported improvements, even if they actually occurred, were to be ascribed to the mixture as a whole rather than to any one of its constituents. As a result of these findings, the Council voted that Dioradin be refused recognition and that the publication of these facts be authorized. In accordance with its regular procedure, it also submitted the report to the agent. In reply the agent submitted evidence which showed that he was not responsible for the misstatements about Dioradin but offered no facts that affected the Council’s findings. The entire matter having been referred to a second referee, minor modifications of the first draft of the report were authorized. Since then the Dioradin Company has submitted two reports of examinations of Dioradin made for the company in Germany showing a higher radium content than that previously found. These reports do not alter the facts brought out in the report of the Council that the composition of Dioradin has been variable, which past variability arouses a feeling of uncertainty or lack of confidence. In view of this the amended report was ordered published and appears below. W. A. Puckner, Secretary. _FIRST SUBMISSION OF DIORADIN_ Dioradin, a preparation for the treatment of consumption originated by Dr. R. de Szendeffy, Budapest, Hungary, was submitted to the Council by Louis Gero, Ltd., New York, with the following statement of composition: “A radio-active preparation of Menthol, Iodin and Radium Barium Chlorid 1/10 of a drop; in ether solution.” A circular which accompanied the submission stated: “Preparation No. 3 of Dioradin contains not only terpins but also iodin salts.... In view of the fact that emanations of the radium as well as the combinations of the evasive iodin terpins enter into the organism through the lung....” Later these indefinite statements of composition were supplemented by the following: “In 100 c.c. there are: 1 gr. Iodoform. 5 " Menthol. 10 drops Radium chlorid solution (1 milligr. in 100 c.c. of water). 5 gr. ether. 90 " Oil (ol. amygd. frig. press).”