The Propaganda for Reform in Proprietary Medicines, Vol. 2 of 2Council on Pharmacy and Chemistry (American Medical Association)
Science
The Propaganda for Reform in Proprietary Medicines, Vol. 2 of 2
Council on Pharmacy and Chemistry (American Medical Association)
Patent medicines
The foregoing citations are obviously intended largely for the public,
and make it plain that “K-Y” Jelly is not in the class of nonmedical
and harmless external applications; on the contrary, these claims
tend to create the impression that the spread of measles and scarlet
fever can be _prevented_ in the stage of desquamation. To place
such statements in the hands of the patient supported by the tacit
endorsement of a prescription is to create a false and dangerous
sense of security and to lead to a failure to observe other and more
important means of preventing dissemination of these diseases.
The Council held K-Y Lubricating Jelly in conflict with Rules 1, 4, 6
and 10, and authorized publication of this report.--(_From The Journal
A. M. A., Sept. 29, 1917._)
ZIRATOL
Report of the Council on Pharmacy and Chemistry
Ziratol (Bristol-Myers Company, New York), in compliance with the
federal “insecticide law,” is declared to contain 32 per cent. water
and 30 per cent. glycerin as inert constituents. Regarding its active
constituents the manufacturer makes the following and meaningless
statement:
“Ziratol is prepared from Phenols of the Naphthalene series and
consists of a solution of such Phenols in a mixture of soap, water and
glycerin.”
In response to inquiry, the A. M. A. Chemical Laboratory examined
Ziratol and reported that its essential constituent appears to be
alpha-napthol,[120] and that it has, essentially, the following
composition by weight: Alpha-napthol 18 per cent., soap 20 per cent.,
glycerin and water sufficient to make 100 per cent.
[120] Alpha-napthol was also found to be the basis
of the nostrum Benetol. See The Journal, April 15,
1911, p. 1128.
A Ziratol advertising circular gives a tabulated report of germicidal
tests, said to have been made according to the method of the Hygienic
Laboratory of the U. S. Public Health Service. When this work was
done is not stated. According to these tests Ziratol possesses a
phenol-coefficient of 13.66. The claim that Ziratol is ten times more
efficient than carbolic acid (phenol) is evidently based on this report.
These claims of high germicidal value are contradicted by an
examination made for the Council. A specimen purchased in the open
market was examined independently by two operators, to determine the
Hygienic Laboratory phenol-coefficient. One observer found the phenol
coefficient to be 2.54. The other reported it to be 3.09. Evidently the
germicidal value of Ziratol is greatly exaggerated in the advertising
claims and, in fact, does not exceed that of the official compound
solution of cresol (Liquor Cresolis Compositus, U. S. P.) for which
a phenol-coefficient of about three has been established. (See New
and Nonofficial Remedies, 1917, p. 82.) The claim that Ziratol is
“the Universal Antiseptic and Germicide” is manifestly an unwarranted
exaggeration.
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