The Propaganda for Reform in Proprietary Medicines, Vol. 2 of 2Council on Pharmacy and Chemistry (American Medical Association)
Science
The Propaganda for Reform in Proprietary Medicines, Vol. 2 of 2
Council on Pharmacy and Chemistry (American Medical Association)
Patent medicines
The referee in submitting this report to the Council recommended that
Ziratol be held in conflict with Rule 1 (secrecy of composition) and
Rule 6 (unwarranted and exaggerated claims). After the report had been
submitted, it was found that a new advertising circular, accompanying
a trade package, no longer contained the claim that “Ziratol is ten
times more efficient than Carbolic Acid.” The older circular made the
following statement:
“1. Strong Activity.--Compared with the bactericidal action of
Carbolic Acid by the method of the Hygienic Laboratory of the
Marine Hospital Service, ZIRATOL has the Carbolic Acid Coefficient
of more than TEN, that is, ZIRATOL is TEN times more efficient than
Carbolic Acid,--a strength unapproached by any other of its class.
ZIRATOL in dilution of 1:1400 kills the Typhoid Bacillus in 2-1/2
minutes, thus proving that it is strongly active even in very weak
solutions.”
The new advertising circular reads:
“1. Strong Activity--Extensive bacteriological investigations on
many pathogenic organisms, conducted in the Lederle Laboratories of
New York, prove conclusively the high bactericidal value of Ziratol
in extremely dilute solutions. (A copy of the complete report will
be mailed upon request.)”
In response to a request, the Bristol-Myers Company sent a copy of
the bacteriologic investigations of Ziratol, said to have been made
by the Lederle Laboratories. The organisms employed for these tests
were _Staphylococcus aureus_, _Staphylococcus albus_, _Streptococcus_,
Green pus bacillus, _B. coli_, and saliva. No tests are given with the
typhoid bacillus. The conclusion is reached that “in all the tests the
solutions of Ziratol have several times greater killing efficiency
than those of phenol.” The “coefficients” or comparative values which
can be calculated from the results after exposure of 15 minutes to the
disinfectants range from 2.0 to 4.0. This is in substantial accord
with the referee’s findings as regards the phenol-coefficient with _B.
typhosus_ as the test object. While the new advertising circular avoids
the former claim that Ziratol is ten times more efficient than carbolic
acid, in germicidal value, it still makes the unwarranted claims that
Ziratol is the “universal disinfectant.”
The Council declared Ziratol inadmissible to New and Nonofficial
Remedies (1) because its composition is secret (Rule 1); (2) because
the phenol coefficient, determined according to the method of the
Hygienic Laboratory, U. S. P. H. S., is not stated on the label (Rule
2); (3) because the label and the circular accompanying the trade
package advises its use by the public as a “vaginal douche” (Rule 3);
and (4) because the claim that Ziratol is the “universal disinfectant”
is exaggerated and unwarranted (Rule 6).
Public-domain text, read in full here on John Shaqi.
Reviews
Reviews
No reviews yet
Be the first to share your thoughts on this work.
Elsewhere in the archive
Join the Discussion
Join the discussion
Sign in to leave a comment or review.
Sign InorCreate an account