The Propaganda for Reform in Proprietary Medicines, Vol. 2 of 2Council on Pharmacy and Chemistry (American Medical Association)
Science
The Propaganda for Reform in Proprietary Medicines, Vol. 2 of 2
Council on Pharmacy and Chemistry (American Medical Association)
Patent medicines
The citations imply that this “colloidal iodin” of Iodeol and
Iodagol acts as an antiseptic like ordinary iodin, except that it is
claimed to be more efficient by “diffusing” more readily. This is
entirely unjustified and misleading. If Iodeol and Iodagol are really
antiseptic, they must act by some other mechanism than that through
which elementary iodin acts, and such antiseptic action would have to
be demonstrated by direct observation and not assumed from the known
action of free iodin.
Antiseptic and bactericidal effects are easily estimated by laboratory
methods. Yet no evidence on this point appeared to have been available
until the Council called for this. Laumonnier then carried out some
experiments which were in turn submitted to bacteriologic control. The
bacteriologist failed to obtain any results with some of the tests, and
considered the other data of little value.
The claim that Iodeol and Iodagol have the antiseptic and bactericidal
action of free iodin lacks proof and must be considered unwarranted and
misleading in the extreme.
_VI. Clinical Trials._--The manufacturers and agents of Iodeol
presented many letters from physicians; but few, if any, of these gave
evidence of careful, critical, controlled observations. They could not,
therefore, be considered as acceptable evidence. The more important
claims, letters and published papers, however, were submitted to
clinical specialists collaborating with the Council, with the request
that they examine these and conduct some clinical trials, if they
considered it advisable. The results obtained in these preliminary
trials did not appear sufficient to warrant further experimentation.
From a consideration of the evidence presented, the referee concludes
that the claims made for Iodeol and Iodagol are unwarranted,
exaggerated and misleading. He recommends that Iodeol and Iodagol be
declared ineligible for New and Nonofficial Remedies for conflict
with Rules 1 and 2 (misleading statements as to composition and
identification) and with Rule 6 (unwarranted and misleading therapeutic
claims). He further recommends that the Council authorize publication
of the preceding summary of the consideration of Iodeol and Iodagol
in The Journal and inclusion of the full report in the annual Council
reports after submission to the manufacturer.--(_From The Journal
A. M. A., Nov. 17, 1917._)
CAPSULES BISMUTH RESORCINOL COMPOUND NOT ADMITTED TO N. N. R.
Report of the Council on Pharmacy and Chemistry
In response to inquiries received, the Council took up the
consideration of Capsules Bismuth Resorcinol Compound (The Gross Drug
Company, Inc., New York City). The label, sent by the Gross Drug
Company, bore the following:
CAPSULES
BISMUTH RESORCINOL COMPOUND
Bismuth Subgallate 2 grs.
Resorcinol 1 gr.
Beta Naphthol 1/2 gr.
Creosote (Beechwood) 1 m.
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