The Propaganda for Reform in Proprietary Medicines, Vol. 2 of 2Council on Pharmacy and Chemistry (American Medical Association)
Science
The Propaganda for Reform in Proprietary Medicines, Vol. 2 of 2
Council on Pharmacy and Chemistry (American Medical Association)
Patent medicines
It is not necessary to quote further. In order to insure that everyone
will recognize the great need of Kalak it is advised to test the urine
for acidity by means of a group of indicator solutions sent out to the
physicians. Methyl red is one of these and any urine showing an acid
reaction with this is said to be open to suspicion. Paranitrophenol is
another of the indicators and the explanations given of the behavior of
the two and the conclusions to be drawn are questionable. The methyl
red solution furnished is too concentrated for proper use and perfectly
normal urines from normal individuals have given a rather marked color
with it. This indicator gives some color at [H+] = 1.2 × 10^{-6} and a
strong reaction at 3 × 10^{-3}. To condemn a urine on such a finding is
entirely unwarranted.
Sodium bicarbonate is the main constituent of the water. The value
of the phosphate in such a combination, with so much calcium, is
problematical. In case an alkaline reaction in the intestine is reached
some of it would be left as insoluble phosphate. A few grams of
bicarbonate daily would have equal therapeutic value with this water.
The advice based on the indications of methyl red and the urine is bad.
The committee’s report was sent to the Kalak Water Company for comment.
The company promised to withdraw the advertising circular referred to
in the report and disclaimed responsibility for the accuracy and value
of the set of indicators which it sent out, but, on the whole, the
previous advertising claims were insisted on.
In view of the absurd and false claims made for the product the Council
declared Kalak Water inadmissible to N. N. R.--(_From Reports of
Council on Pharmacy and Chemistry, 1917, p. 148._)
MINSON’S SOLUBLE IODIN “KELPIDINE” NOT ADMITTED TO N. N. R.
Report of the Council on Pharmacy and Chemistry
Minson’s Soluble Iodin “Kelpidine” was submitted to the Council by
J. J. Minson, Washington, D. C., trading as the Kelpidine Company,
with the statement that in future “literature” it was to be known as
Minson’s Soluble Iodin, only. The following statement of composition
was furnished:
“Minson’s Soluble Iodin is somewhat of an indefinite character,
chemically. Its formula is, Iodin 4 per cent., Distilled Water
6 per cent., and Absolute Alcohol _q. s._ 100 per cent. By a
process of chilling and heating an iodid of uncertain character is
produced, and because of the extreme sensitiveness of the product
to chemical tests, it is hard to determine. So far as I have been
able to judge, however, the result is about 3 or 3-1/2 per cent.
free iodin and from 1/2 per cent. to 1 per cent. iodid, possibly
ethyl and hydrogen iodid in combination.”
The A. M. A. Chemical Laboratory reports that the preparation is an
alcoholic solution containing free iodin and iodid, probably hydrogen
iodid and ethyl iodid, but that the free iodin content was only
2.69 gm. per 100 c.c.
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