The Propaganda for Reform in Proprietary Medicines, Vol. 2 of 2Council on Pharmacy and Chemistry (American Medical Association)
Science
The Propaganda for Reform in Proprietary Medicines, Vol. 2 of 2
Council on Pharmacy and Chemistry (American Medical Association)
Patent medicines
“Has odor, taste, melting and boiling point, same as regular
Iodin, has a great affinity for water and will respond to all
the tests of Iodin. Appears in a Bluish Black Granulated mass or
Powder. When heated in vaporating dish will throw off large purple
volumes of Iodin leaving a slight white crystalline precipitate,
which on continuous heating will entirely disappear. With careful
manipulation you can get prismatic needle point like crystals,
looking like spores of glass, these dissolving in water will yield
pure Iodin coloring the water Iodin.
“PHARMACOLOGIC, THERAPEUTICAL AND PHYSIOLOGICAL ACTION: Same as
Iodin, being of a colloidal nature has the advantage of being more
readily absorbed and taken up by all cellular structure, thus
getting a perfect cellular medication of Iodin.”
A sample of B. Iodine, marked “Nitrogen Hydrate of Iodin” was submitted
by the manufacturers and this sample was examined.
B. Iodine was found to be a granular powder, almost black with a purple
cast. It has an odor of iodin and dissolves in water readily. It is
also quite soluble in alcohol, but not entirely soluble in chloroform
and ether. Ether quickly dissolves iodin from B. Iodine, leaving a
residue of a white granular substance. Chloroform acts the same as
ether except that the iodin is dissolved out with some difficulty. On
heating B. Iodine, vapors of iodin escape. If the heating is done on
a water bath, a residue of a white granular substance, subsequently
identified as ammonium iodid, remains. If heated in a bunsen flame, no
residue remains. These tests all indicate that iodin is held in the
form of a simple mixture.
_Ammonia_: B. Iodine when mixed with an excess of sodium hydroxid and
warmed, evolves ammonia.
_Iodine_: 0.1567 gm. B. Iodine dissolved in water required 5.88 c.c.
tenth-normal sodium thiosulphate solution indicating 48.28 per cent.
iodin. 0.3721 gm. B. Iodine required 14.18 c.c. tenth-normal sodium
thiosulphate solution indicating 48.37 per cent. iodin. The average is
48.33 per cent. iodin.
_Ammonium Iodide_: 0.3453 gm. of the residue after heating B. Iodine on
a water bath until all iodin had volatilized was dissolved in water,
acidulated with phosphoric acid, and hydrogen dioxid solution added.
The liberated iodin was extracted with chloroform and titrated with
tenth-normal sodium thiosulphate. 23.78 c.c. were required indicating
0.3447 gm., or 99.83 per cent., ammonium iodid.
A mixture of 5 gm. iodin and 5 gm. ammonium iodid has the properties of
B. Iodine mentioned above.
The conclusion is that B. Iodine is essentially a mixture of iodin and
ammonium iodid in equal parts, the two substances being finely powdered
and intimately mixed.
B. OLEUM IODINE
The following regarding B. Oleum Iodine is quoted from the circular
submitted:
Public-domain text, read in full here on John Shaqi.
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